Biobehavioral determinants of glycemic control in type 2 diabetes: A systematic review and meta-analysis.

Biobehavioral determinants of glycemic control in type 2 diabetes: A systematic review and meta-analysis.
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DOI:
10.1016/j.pec.2016.03.020
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发表时间:
2016-10
影响因子:
3.5
通讯作者:
Cuevas HE
Cuevas HE
中科院分区:
医学2区
文献类型:
--
作者:
Brown SA;García AA;Brown A;Becker BJ;Conn VS;Ramírez G;Winter MA;Sumlin LL;Garcia TJ;Cuevas HE

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对糖尿病结局的心理和动机预测因素的相关性研究进行模型驱动的荟萃分析,并以依从性因素为中介。对已发表和未发表的研究进行了全面的文献检索,找到了739份研究报告中报告的775项个体相关性或预测性研究的样本。结果因回归模型中包含的结果变量而异。抑郁症对坚持体力活动的负面影响大于对饮食的影响。应对和自我效能与饮食依从性密切相关,饮食依从性与血糖控制改善密切相关。药物依从性与糖化血红蛋白相关,而药物和自我监测与空腹血糖相关。在模型中加入预约并没有显著改变结果。自我效能是所有依从性行为的最一致预测因子,饮食依从性是HbA1c的最显著预测因子。体力活动是BMI的最佳预测因素,血糖自我监测是FBG的最佳预测因素。代谢控制是T2DM的主要目标,因此实现该目标的最佳途径似乎是强调自我效能和饮食依从性。
To conduct a model-driven meta-analysis of correlational research on psychological and motivational predictors of diabetes outcomes, with adherence factors as mediators. A comprehensive literature search of published and unpublished studies located a sample of 775 individual correlational or predictive studies reported across 739 research reports. Results varied according to the outcome variable included in the regression models. Depression had a larger negative effect on adherence to physical activity than on dietary adherence. Coping and self-efficacy were strongly related to dietary adherence, which was strongly related to improved glycemic control. Medication adherence was related to glycosylated hemoglobin, whereas medications and self-monitoring were related to fasting blood glucose. Adding appointment keeping to the models did not significantly alter the results. Self-efficacy was the most consistent predictor of all adherence behaviors and dietary adherence was the most significant predictor of HbA1c. Physical activity was the most predictive factor of BMI and glucose self-monitoring the most predictive of FBG. Metabolic control is a primary goal in T2DM, so the best pathway to attaining that goal appears to be an emphasis on self-efficacy and dietary adherence.
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