Implementation of a new cost efficacy method for blood irradiation using a non dedicated device.
Implementation of a new cost efficacy method for blood irradiation using a non dedicated device.
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DOI：
10.1186/1756-9966-30-7
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发表时间：
2011-01-12
期刊：
影响因子：
--
通讯作者：
Strigari L
中科院分区：
文献类型：
--
作者：
Pinnarò P;Soriani A;D'Alessio D;Giordano C;Foddai ML;Pinzi V;Strigari L
为了实施一项新的具有成本效益的血液成分辐照内部服务，我们使用Regina Elena研究所（IRE）放射治疗部的线性加速器（LINACs）而不是专用设备进行了具体的程序和质量保证报告。已经确定了建立当地辐照血库的内部程序的技术方面、质量保证和监管要求。使用IRE放射治疗科的LINACs提供32 Gy的平均剂量，并使用变色膜检查剂量准确性。将该程序的总时间/成本与之前的程序进行比较，将血液成分的辐照外包。第一年共对1996个血液成分单位进行了内部照射。此外，将整个过程的时间减少了三分之一。外部和内部程序的总成本/包约为。分别是66欧元和11欧元。因此，平均每袋节省成本超过80%。在所有辐照过的血液成分袋中使用变色膜，可以检查输送到血液中的剂量的准确性。利用安装在放射治疗科的LINACs，可以提供内部血液成分照射服务，利用内部资源，而不会给接受放射治疗的患者带来任何不便/不适，并满足政府的监管要求。内部照射程序已被证明是安全可行的，并且随着成本/时间的显著减少，表明它比外部照射程序更有利。
To implement a new cost efficacy internal Service for blood component irradiation, we carried out specific procedures and quality assurance reports using the linear accelerators (LINACs) of the Regina Elena Institute (IRE) Radiotherapy Department instead of a dedicated device. The technical aspects, quality assurance and regulatory requirements of the internal procedure to set up a local irradiated blood bank have been defined. The LINACs of the IRE Radiotherapy Department were used to deliver a mean dose of 32 Gy and dose accuracy was checked with gafchromic film. The overall time/cost of this procedure was compared with the previous procedure, out-sourcing the irradiation of blood components. A total of 1996 blood component units were internally irradiated in the first year. Moreover, reducing the overall procedure time by a third. Overall cost/bag of external and internal procedures was approx. 66 € and 11 €, respectively. Thus the average saving of cost/bag was higher than 80%. The use of gafchromic films in all irradiated blood component bags allowed the accuracy of the dose delivered to blood to be checked. By utilizing LINACs installed in the Radiotherapy Department it is possible to provide an internal blood component irradiation service, capitalizing on internal resources without any inconvenience/discomfort to patients undergoing radiotherapy and satisfying governmental regulatory requirements. The internal irradiation procedures has proven to be safe and feasible, and along with the significant cost/time reduction suggests that it is more advantageous than external procedures.
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