Microfluidic proportional flow controller.
Microfluidic proportional flow controller.
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DOI:
10.1088/0960-1317/20/11/115020
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发表时间:
2010-10-15
期刊:
影响因子:
--
通讯作者:
Irimia D
中科院分区:
文献类型:
--
作者:
Prentice-Mott H;Toner M;Irimia D
Precise flow control in microfluidic chips is important for many biochemical assays and experiments at microscale. While several technologies for controlling fluid flow have been implemented either on- or off-chip, these can provide either high-speed or high-precision control, but seldom could accomplish both at the same time. Here we describe a new on-chip, pneumatically activated flow controller that allows for fast and precise control of the flow rate through a microfluidic channel. Experimental results show that the new proportional flow controllers exhibited a response time of approximately 250 ms, while our numerical simulations suggest that faster actuation down to approximately 50 ms could be achieved with alternative actuation schemes.
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