protti: an R package for comprehensive data analysis of peptide- and protein-centric bottom-up proteomics data.
protti: an R package for comprehensive data analysis of peptide- and protein-centric bottom-up proteomics data.
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DOI:
10.1093/bioadv/vbab041
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发表时间:
2022
期刊:
影响因子:
--
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中科院分区:
文献类型:
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We present a flexible, user-friendly R package called protti for comprehensive quality control, analysis and interpretation of quantitative bottom-up proteomics data. protti supports the analysis of protein-centric data such as those associated with protein expression analyses, as well as peptide-centric data such as those resulting from limited proteolysis-coupled mass spectrometry analysis. Due to its flexible design, it supports analysis of label-free, data-dependent, data-independent and targeted proteomics datasets. protti can be run on the output of any search engine and software package commonly used for bottom-up proteomics experiments such as Spectronaut, Skyline, MaxQuant or Proteome Discoverer, adequately exported to table format. protti is implemented as an open-source R package. Release versions are available via CRAN (https://CRAN.R-project.org/package=protti) and work on all major operating systems. The development version is maintained on GitHub (https://github.com/jpquast/protti). Full documentation including examples is provided in the form of vignettes on our package website (jpquast.github.io/protti/).
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DOI:
10.1093/bioinformatics/btw580
发表时间:
2017-01-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Wieczorek S;Combes F;Lazar C;Giai Gianetto Q;Gatto L;Dorffer A;Hesse AM;Couté Y;Ferro M;Bruley C;Burger T
通讯作者:
Burger T
影响因子:
14.9
作者:
Ritchie ME;Phipson B;Wu D;Hu Y;Law CW;Shi W;Smyth GK
通讯作者:
Smyth GK
DOI:
10.1016/j.csbj.2020.06.036
发表时间:
2020-01-01
影响因子:
6
作者:
Minadakis, George;Sokratous, Kleitos;Spyrou, George M.
通讯作者:
Spyrou, George M.
影响因子:
5.8
作者:
van Breukelen, Bas;van den Toorn, Henk W. P.;Heck, Albert J. R.
通讯作者:
Heck, Albert J. R.
影响因子:
4.4
作者:
Shah, Anup D.;Goode, Robert J. A.;Schittenhelm, Ralf B.
通讯作者:
Schittenhelm, Ralf B.