Mental health disorders among ovarian cancer survivors in a population-based cohort.
Mental health disorders among ovarian cancer survivors in a population-based cohort.
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DOI：
10.1002/cam4.4976
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发表时间：
2023-01
期刊：
影响因子：
4
通讯作者：
Hashibe, Mia
中科院分区：
文献类型：
--
作者：
Hu, Siqi;Baraghoshi, David;Chang, Chun-Pin;Rowe, Kerry;Snyder, John;Deshmukh, Vikrant;Newman, Michael;Fraser, Alison;Smith, Ken;Peoples, Anita R.;Gaffney, David;Hashibe, Mia
卵巢癌是美国第五大常见的女性癌症。很少有研究调查卵巢癌幸存者的心理健康诊断，并进行长期随访。本研究的目的是检查卵巢癌幸存者与普通人群队列相比精神疾病的发病率。第二个目的是调查卵巢癌幸存者中精神疾病的危险因素。确定了1996年至2012年期间诊断的1689名卵巢癌患者和7038名年龄和出生状态匹配的普通人群中无癌症的女性。精神健康诊断是从电子病历和全州医疗机构数据中确定的。使用考克斯比例风险模型估计风险比（HR）。卵巢癌幸存者在癌症诊断后的前2年内患精神疾病的风险增加（HR = 3.55，95%CI = 3.04-4.14）。在癌症诊断的前2年内，卵巢癌幸存者的抑郁风险接近3倍（HR = 2.59，95% CI = 1.94-3.47），在癌症诊断后2-5年为1.69倍（HR = 1.69，95% CI = 1.18-2.42）。卵巢癌幸存者因精神疾病诊断而死亡的风险增加80%（HR = 1.80，95% CI = 1.48-2.18），因抑郁症诊断而死亡的风险增加94%（HR = 1.94，95% CI = 1.56-2.40）。在癌症诊断后0-2年和2-5年的随访期间，在卵巢癌幸存者中观察到精神疾病的风险较高。需要多学科护理来监测和治疗卵巢癌幸存者的精神疾病。
Ovarian cancer is the fifth most common female cancer in the United States. There have been very few studies investigating mental health diagnoses among ovarian cancer survivors with long‐term follow up. The aim of this study is to examine the incidence of mental illness among ovarian cancer survivors compared to a general population cohort. A secondary aim is to investigate risk factors for mental illnesses among ovarian cancer survivors. Cohorts of 1689 ovarian cancer patients diagnosed between 1996 and 2012 and 7038 women without cancer matched by age and birth state from the general population were identified. Mental health diagnoses were identified from electronic medical records and statewide healthcare facilities data. Cox proportional hazard models were used to estimate hazard ratios (HRs). Ovarian cancer survivors experienced increased risks of mental illnesses within the first 2 years after cancer diagnosis (HR = 3.55, 95% CI = 3.04–4.14). The risks of depression among ovarian cancer survivors were nearly 3‐fold within the first 2 years of cancer diagnosis (HR = 2.59, 95% CI = 1.94–3.47), and 1.69‐fold at 2–5 years after cancer diagnosis (HR = 1.69, 95% CI = 1.18–2.42). Ovarian cancer survivors experienced an 80% increased risk of death with a mental illness diagnosis (HR = 1.80, 95% CI = 1.48–2.18) and a 94% increased risk of death with a depression diagnosis (HR = 1.94, 95% CI = 1.56–2.40). Higher risks of mental illnesses were observed among ovarian cancer survivors throughout the follow‐up periods of 0–2 years and 2–5 years after cancer diagnosis. Multidisciplinary care is needed to monitor and treat mental illnesses among ovarian cancer survivors.
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影响因子：
4.7
作者：
Hamer, Mark;Chida, Yoichi;Molloy, Gerard J.
通讯作者：
Molloy, Gerard J.
影响因子：
45.3
作者：
Norton, TR;Manne, SL;Bergman, C
通讯作者：
Bergman, C
影响因子：
3.1
作者：
Manderbacka, Kristiina;Arffman, Martti;Pukkala, Eero
通讯作者：
Pukkala, Eero
影响因子：
3.6
作者：
Shand, Lyndel K.;Brooker, Joanne E.;Ricciardelli, Lina A.
通讯作者：
Ricciardelli, Lina A.
DOI：
10.1016/s0140-6736(18)32279-7
发表时间：
2018-11-10
期刊：
Lancet (London, England)
影响因子：
--
作者：
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators
通讯作者：
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators