A dendritic thioester hydrogel based on thiol-thioester exchange as a dissolvable sealant system for wound closure.
A dendritic thioester hydrogel based on thiol-thioester exchange as a dissolvable sealant system for wound closure.
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DOI：
10.1002/anie.201308007
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发表时间：
2013-12-23
影响因子：
16.6
通讯作者：
Grinstaff, Mark W.
中科院分区：
文献类型：
--
作者：
Ghobril, Cynthia;Charoen, Kristie;Rodriguez, Edward K.;Nazarian, Ara;Grinstaff, Mark W.
A dissolvable dendritic thioester hydrogel based on thiol-thioester exchange for wound closure is reported. The hydrogel sealant adheres strongly to tissues, closes an ex vivo vein puncture, and withstands high pressures placed on a wound. The hydrogel sealant can be completely washed off upon exposure to thiolates based on thiol-thioester exchange and allow gradual wound re-exposure during definitive surgical care.
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通讯作者：
Grinstaff, Mark W.
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通讯作者：
Grinstaff MW