Establishing "best practices" for opioid rotation: conclusions of an expert panel.
Establishing "best practices" for opioid rotation: conclusions of an expert panel.
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DOI：
10.1016/j.jpainsymman.2009.06.002
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发表时间：
2009-09
影响因子：
4.7
通讯作者：
Portenoy, Russell K.
中科院分区：
文献类型：
--
作者：
Fine, Perry G.;Portenoy, Russell K.
阿片类药物轮换是在阿片类药物治疗疼痛期间应用的一种策略，指的是从一种阿片类药物转换到另一种阿片类药物，以努力改善临床结果(益处或危害)。它首先选择一种起始剂量的新药，在理想情况下保持止痛效果的同时将潜在风险降至最低。在选择起始剂量时，必须估计现有阿片类药物和新阿片类药物之间的相对效力。临床上对相对止痛效力的估计已编入“等止痛剂剂量表”，该表已使用了40多年，几乎没有任何修改。关于长期阿片类药物治疗慢性疼痛的相对效力和越来越多的实施情况的新信息，为召开专家小组讨论阿片类药物轮换的科学基础以及目前应为这一做法提供临床指南的因素提供了强有力的理由。专家小组肯定了目前等剂量剂量表的价值和局限性，并提出了一项旨在促进阿片类药物轮换期间安全的准则。
Opioid rotation is a strategy applied during opioid therapy for pain that refers to a switch from one opioid to another in an effort to improve clinical outcomes (benefits or harms). It begins with the selection of a new drug at a starting dose that minimizes potential risks while ideally maintaining analgesic efficacy. The selection of a starting dose must be informed by an estimate of the relative potency between the existing opioid and the new one. Clinically relevant estimates of relative analgesic potency have been codified on the “equianalgesic dose table,” which has been used with little modification for more than 40 years. New information about relative potency and the growing implementation of long-term opioid therapy for chronic pain provided a strong rationale for the convening of an expert panel to discuss the scientific foundation to opioid rotation and the elements that now should inform a clinical guideline for this practice. The panel affirmed both the value and the limitations of the current equianlagesic dose table and proposed a guideline intended to promote safety during opioid rotation.
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DOI：
10.1016/j.jpain.2008.10.008
发表时间：
2009-02
期刊：
The journal of pain
影响因子：
--
作者：
Chou R;Fanciullo GJ;Fine PG;Adler JA;Ballantyne JC;Davies P;Donovan MI;Fishbain DA;Foley KM;Fudin J;Gilson AM;Kelter A;Mauskop A;O'Connor PG;Passik SD;Pasternak GW;Portenoy RK;Rich BA;Roberts RG;Todd KH;Miaskowski C;American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
通讯作者：
American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
影响因子：
45.3
作者：
Ripamonti, C;Groff, L;De Conno, F
通讯作者：
De Conno, F
影响因子：
3.6
作者：
Shi, Jie;Zhao, Li-Yan;Lu, Lin
通讯作者：
Lu, Lin
影响因子：
4.7
作者：
Pereira, J;Lawlor, P;Bruera, E
通讯作者：
Bruera, E
影响因子：
6.2
作者：
Lawlor, PG;Turner, KS;Bruera, ED
通讯作者：
Bruera, ED