Egg Allergy in US Children.
Egg Allergy in US Children.
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DOI：
10.1016/j.jaip.2020.04.058
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发表时间：
2020-10
期刊：
影响因子：
--
通讯作者：
Gupta RS
中科院分区：
文献类型：
--
作者：
Samady W;Warren C;Wang J;Das R;Gupta RS
鸡蛋过敏在幼儿(<；5岁)中很常见，对生活质量有显著的负面影响。这项研究的目的是在一个庞大的美国队列中描述鸡蛋过敏的流行率、严重程度、烤鸡蛋耐受性和其他相关因素。2015年10月至2016年9月进行了一项全国横断面调查，对38408名儿童进行了完整的父母代理调查。估计加权比例，以比较鸡蛋过敏患病率和关键亚群之间的特征。目前，令人信服的鸡蛋过敏总体患病率在所有儿童中为0.9%，在5岁儿童中为1.3%。在鸡蛋过敏的儿童中，黑人儿童的比例过高，占鸡蛋过敏儿童的23.4%(95%CI：13.1-38.4)，尽管占美国儿科人口的13.2%(12.3-14-2)。在鸡蛋过敏的儿童中，64.2%的儿童报告对烤鸡蛋耐受，60.2%的儿童对其他食物过敏，其中29.3%的儿童对花生过敏。与其他前8名食物过敏儿童相比，鸡蛋过敏儿童哮喘的发生率更高(46.5%，35.8-57.4比33.2%，29.6-37.0，p<；0.05)。在目前的鸡蛋过敏儿童中，那些有烘焙鸡蛋耐受性的儿童报告说，与对烘焙鸡蛋过敏的儿童相比，他们的食物过敏导致的心理社会负担显著减少(M=3.1(2.9-3.3)vs M=3.7(3.5-3.9))。鸡蛋过敏在幼儿中很常见。近三分之二的鸡蛋过敏儿童报告说对烤鸡蛋有耐受性。需要做出更多的努力来确保对鸡蛋过敏的儿童进行适当的评估，因为许多儿童都患有过敏性疾病，而确定烤鸡蛋的耐受性可能会改善生活质量。
Egg allergy is common in young children (<5 years) and has significant negative impacts on quality of life. The objective of this study was to characterize egg allergy prevalence, severity, baked egg tolerance, and other associated factors in a large US cohort. A national cross-sectional survey was administered from October 2015-September 2016, resulting in complete parent-proxy responses for 38,408 children. Weighted proportions were estimated to compare egg allergy prevalence and characteristics between key subpopulations. Overall prevalence of current, convincingly egg allergy was 0.9% among all children and 1.3% among children <5 years. Black children were over-represented among children with egg allergy, accounting for 23.4% (95% CI: 13.1–38.4) of egg-allergic children despite comprising 13.2% (12.3-14-2) of the US pediatric population. Among children with egg allergy, 64.2% reported baked egg tolerance and 60.2% had allergy to other foods, with 29.3% having peanut allergy. Asthma was more prevalent in children with an egg allergy than children with other top 8 food allergies (46.5%, (35.8–57.4) vs 33.2% (29.6–37.0), p<0.05). Among children with current egg allergy, those with baked egg tolerance reported that their food allergy resulted in significantly reduced psychosocial burden, relative to their baked egg-allergic counterparts (M=3.1 (2.9–3.3) vs M=3.7 (3.5–3.9). Egg allergy is common amongst young children. Nearly two-thirds of children with egg allergy reported baked egg tolerance. Increased efforts are needed to ensure children with egg allergy are appropriately evaluated as many have comorbid allergic disease and determination of baked egg tolerance may improve QoL.
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DOI：
10.1016/j.jaip.2017.10.019
发表时间：
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影响因子：
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作者：
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