2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups.
2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups.
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DOI：
10.1136/annrheumdis-2017-211468
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发表时间：
2017-12
影响因子：
27.4
通讯作者：
International Myositis Classification Criteria Project consortium, The Euromyositis register and The Juvenile Dermatomyositis Cohort Biomarker Study and Repository (JDRG) (UK and Ireland)
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文献类型：
--
作者：
Lundberg IE;Tjärnlund A;Bottai M;Werth VP;Pilkington C;Visser M;Alfredsson L;Amato AA;Barohn RJ;Liang MH;Singh JA;Aggarwal R;Arnardottir S;Chinoy H;Cooper RG;Dankó K;Dimachkie MM;Feldman BM;Torre IG;Gordon P;Hayashi T;Katz JD;Kohsaka H;Lachenbruch PA;Lang BA;Li Y;Oddis CV;Olesinska M;Reed AM;Rutkowska-Sak L;Sanner H;Selva-O'Callaghan A;Song YW;Vencovsky J;Ytterberg SR;Miller FW;Rider LG;International Myositis Classification Criteria Project consortium, The Euromyositis register and The Juvenile Dermatomyositis Cohort Biomarker Study and Repository (JDRG) (UK and Ireland)
制定并验证成人和青少年特发性炎症性肌病 (IIM) 及其主要亚组的新分类标准。候选变量是使用共识方法根据已发布的标准和专家意见组合而成的。数据收集自全球 47 个风湿病学、皮肤病学、神经病学和儿科诊所。使用多种统计方法来得出分类标准。根据 976 名 IIM 患者（74% 成人；26% 儿童）和 624 名具有模仿症状的非 IIM 患者（82% 成人；18% 儿童）的数据，得出了新标准。每个项目都分配一个加权分数。总分对应于患有 IIM 的概率。使用分类树执行子分类。 55% 的概率截止值，对应于 5.5 分（肌肉活检为 6.7）“可能的 IIM”，具有最佳敏感性/特异性（无活检时为 87%/82%，有活检时为 93%/88%），建议作为将患者分类为 IIM 的最低值。 ≥90% 的概率，对应于评分≥7.5（肌肉活检≥8.7），对应于“确定的 IIM”。 <50% 的概率，对应于 <5.3 的分数（肌肉活检<6.5）排除 IIM，留下 ≥50 至 <55% 的概率为“可能的 IIM”。 IIM 的 EULAR/ACR 分类标准已得到国际风湿病学、皮肤病学、神经病学和儿科团体的认可。它们采用易于访问和可操作定义的元素，并且已经过部分验证。除了 IIM 的主要亚组（包括青少年 IIM）之外，它们还允许对“确定的”、“可能的”和“可能的”IIM 进行分类。它们的表现通常优于现有标准。
To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. Candidate variables were assembled from published criteria and expert opinion using consensus methodology. Data were collected from 47 rheumatology, dermatology, neurology and pediatric clinics worldwide. Several statistical methods were utilized to derive the classification criteria. Based on data from 976 IIM patients (74% adults; 26% children) and 624 non-IIM patients with mimicking conditions (82% adults; 18% children) new criteria were derived. Each item is assigned a weighted score. The total score corresponds to a probability of having IIM. Sub-classification is performed using a classification tree. A probability cutoff of 55%, corresponding to a score of 5.5 (6.7 with muscle biopsy) “probable IIM”, had best sensitivity/specificity (87%/82% without biopsies, 93%/88% with biopsies) and is recommended as a minimum to classify a patient as having IIM. A probability of ≥90%, corresponding to a score of ≥7.5 (≥8.7 with muscle biopsy), corresponds to “definite IIM”. A probability of <50%, corresponding to a score of <5.3 (<6.5 with muscle biopsy) rules out IIM, leaving a probability of ≥50 to <55% as “possible IIM”. The EULAR/ACR classification criteria for IIM have been endorsed by international rheumatology, dermatology, neurology and pediatric groups. They employ easily accessible and operationally defined elements, and have been partially validated. They allow classification of “definite”, “probable”, and “possible” IIM, in addition to the major subgroups of IIM, including juvenile IIM. They generally perform better than existing criteria.
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影响因子：
2.3
作者：
Mastaglia, FL;Phillips, BA
通讯作者：
Phillips, BA
影响因子：
5
作者：
Ruperto, Nicolino;Meiorin, Silvia;Martini, Alberto
通讯作者：
Martini, Alberto
影响因子：
9.9
作者：
Lloyd, Thomas E.;Mammen, Andrew L.;Greenberg, Steven A.
通讯作者：
Greenberg, Steven A.
影响因子：
4.7
作者：
Aggarwal, Rohit;Ringold, Sarah;Khanna, Dinesh;Neogi, Tuhina;Johnson, Sindhu R.;Miller, Amy;Brunner, Hermine I.;Ogawa, Rikke;Felson, David;Ogdie, Alexis;Aletaha, Daniel;Feldman, Brian M.
通讯作者：
Feldman, Brian M.
影响因子：
158.5
作者：
BOHAN, A;PETER, JB
通讯作者：
PETER, JB