The relationship between coping strategies, quality of life, and mood in patients with incurable cancer.
The relationship between coping strategies, quality of life, and mood in patients with incurable cancer.
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DOI：
10.1002/cncr.30025
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发表时间：
2016-07-01
期刊：
影响因子：
6.2
通讯作者：
Temel, Jennifer S.
中科院分区：
文献类型：
--
作者：
Nipp, Ryan D.;El-Jawahri, Areej;Fishbein, Joel N.;Eusebio, Justin;Stagl, Jamie M.;Gallagher, Emily R.;Park, Elyse R.;Jackson, Vicki A.;Pirl, William F.;Greer, Joseph A.;Temel, Jennifer S.
癌症不治之症患者面临着许多生理和情感压力，但人们对他们的应对策略或他们的应对策略、生活质量和情绪之间的关系知之甚少。作为姑息治疗随机试验的一部分，这项研究评估了患者在被诊断为不可治愈的肺癌或胃肠道癌症后8周内和随机之前的基线生活质量(癌症治疗功能评估-普通)、情绪(医院焦虑和抑郁量表)和应对(简短应对)。为了检验应对策略、生活质量和情绪之间的关系，我们使用了线性回归，对患者的年龄、性别、婚姻状况和癌症类型进行了调整。共有350名参与者(平均年龄64.9岁)，大多数是男性(54.0%)，已婚(70.0%)，患有肺癌(54.6%)。大部分被调查者对情感支持的利用度较高(77.0%)，而较少的被调查者报告对接纳(44.8%)、自责(37.9%)和否认(28.2%)有较高的利用度。情绪支持(生活质量：β=2.65，P&t；01；抑郁：β=−0.56，P=0.02)和接受(生活质量：β=1.55，P&t；0.01；抑郁：β=−0.37，P=0.01；焦虑：β=−0.34，P=0.02)与较好的生活质量和情绪相关。否认(生活质量：β=−1.97，P&t；01；抑郁：β=0.36，P=.01；焦虑：β=0.61，P<；.01)和自责(生活质量：β=−2.31，P&t；.01；抑郁：β=0.58，P&t；.01；焦虑：β=0.66，P<；.01)与较差的生活质量和情绪有关。新诊断的、无法治愈的癌症患者使用各种应对策略。情绪支持和接纳应对策略的使用与更好的生活质量和情绪相关，而否认和自责的使用与这些结果负相关。改善患者生活质量和情绪的干预措施应努力培养适应性应对策略的使用。被新诊断为不治之症的患者以各种独特的方式应对。我们发现，患者使用某些应对策略与他们的生活质量和情绪相关，这表明评估和解决患者的应对行为可能会影响患者报告的其他关键结果。
Patients with incurable cancer face many physical and emotional stressors, yet little is known about their coping strategies or the relationship between their coping strategies, quality of life (QOL) and mood. As part of a randomized trial of palliative care, this study assessed baseline QOL (Functional Assessment of Cancer Therapy–General), mood (Hospital Anxiety and Depression Scale), and coping (Brief COPE) in patients within 8 weeks of a diagnosis of incurable lung or gastrointestinal cancer and before randomization. To examine associations between coping strategies, QOL, and mood, we used linear regression, adjusting for patients’ age, sex, marital status, and cancer type. There were 350 participants (mean age, 64.9 years), and the majority were male (54.0%), were married (70.0%), and had lung cancer (54.6%). Most reported high utilization of emotional support coping (77.0%), whereas fewer reported high utilization of acceptance (44.8%), self-blame (37.9%), and denial (28.2%). Emotional support (QOL: β = 2.65, P < .01; depression: β = −0.56, P = .02) and acceptance (QOL: β = 1.55, P < .01; depression: β = −0.37, P = .01; anxiety: β = −0.34, P = .02) correlated with better QOL and mood. Denial (QOL: β = −1.97, P < .01; depression: β = 0.36, P = .01; anxiety: β = 0.61, P < .01) and self-blame (QOL: β = −2.31, P < .01; depression: β = 0.58, P < .01; anxiety: β = 0.66, P < .01) correlated with worse QOL and mood. Patients with newly diagnosed, incurable cancer use a variety of coping strategies. The use of emotional support and acceptance coping strategies correlated with better QOL and mood, whereas the use of denial and self-blame negatively correlated with these outcomes. Interventions to improve patients’ QOL and mood should seek to cultivate the use of adaptive coping strategies. Patients with a new diagnosis of incurable cancer cope in a variety of unique ways. We found that patients’ use of certain coping strategies correlated with their QOL and mood, suggesting that evaluating and addressing patients’ coping behaviors may impact other key patient-reported outcomes.
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影响因子：
45.3
作者：
Brundage, MD;Davidson, JR;Mackillop, WJ
通讯作者：
Mackillop, WJ
影响因子：
3.3
作者：
Kitano, Atsuko;Yamauchi, Hideko;Tsunoda, Hiroko
通讯作者：
Tsunoda, Hiroko
影响因子：
3.6
作者：
Loi, Claudia X. Aguado;Baldwin, Julie A.;VandeWeerd, Carla
通讯作者：
VandeWeerd, Carla
影响因子：
6.2
作者：
Lutgendorf, SK;Anderson, B;Ritchie, J
通讯作者：
Ritchie, J
影响因子：
3.6
作者：
Costanzo, ES;Lutgendorf, SK;Anderson, B
通讯作者：
Anderson, B