Interactions between heparan sulfate and proteins: the concept of specificity.
Interactions between heparan sulfate and proteins: the concept of specificity.
复制标题
硫酸乙酰肝素与蛋白质之间的相互作用:特异性的概念。
DOI:
10.1083/jcb.200604035
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发表时间:
2006-07-31
影响因子:
7.8
通讯作者:
Lindahl, Ulf
中科院分区:
文献类型:
--
作者:
Kreuger, Johan;Spillmann, Dorothe;Li, Jin-ping;Lindahl, Ulf
Proteoglycan (PG) coreceptors carry heparan sulfate (HS) chains that mediate interactions with growth factors, morphogens, and receptors. Thus, PGs modulate fundamental processes such as cell survival, division, adhesion, migration, and differentiation. This review summarizes recent biochemical and genetic information that sheds new light on the nature of HS–protein binding. Unexpectedly, many interactions appear to depend more on the overall organization of HS domains than on their fine structure.
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影响因子:
7.8
作者:
Ai, Xingbin;Do, Anh-Tri;Lozynska, Olga;Kusche-Gullberg, Marion;Lindahl, Ulf;Emerson, Charles P Jr
通讯作者:
Emerson, Charles P Jr
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11.8
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通讯作者:
Kimata, K