Making the invisible visible: improving conspicuity of noncalcified gallstones using dual-energy CT
Making the invisible visible: improving conspicuity of noncalcified gallstones using dual-energy CT
复制标题
化无形为可见：利用双能 CT 提高非钙化胆结石的清晰度
作者：
Jennifer W. Uyeda;Ian J. Richardson;A. Sodickson
PurposeTo determine whether virtual monochromatic imaging（VMI）increases detectability of noncalcified challenges on dual-energy CT（DECT）compared to conventional CT imaging.Materials and methodsThis retrospective IRB approved，HIPAA-compliant study includes continuous patients who encountered DECT of the abdomen in Emergency Department during a 30 month period（2013年7月1日至2015年12月31日），与1年内的US或MR进行比较。51例患者（36例女性，15例男性;平均年龄52岁）符合入选标准。所有DECT均在双源128 × 2切片扫描仪上使用80/Sn 140或100/Sn 140 kVp对采集。在高和低kVp下的源图像用于采用VMI的DE后处理。在3 mm重建图像，感兴趣的区域0.5 cm 2被放置在非钙化的胆结石和胆汁记录hounsfield单位（HU）在VMI能量水平范围在40和190 keV.ResultsNoncalcified胆结石均匀地表现出最低的HU在40 keV和增加在较高的keV;在较高的keV的胆汁的HU变化。在70 keV（模拟传统的120 kVp扫描）下，几乎没有非钙化结石可见，78%的患者测量的对比度（胆结石HU差异）<10 HU，20%为10-20 HU，2%为>20 HU。对比度在40 keV时最大，其中100%显示与周围胆汁的差异>20 HU，75% >44 HU差异，50% >60 HU差异。配对t检验表明，在40与70 keV和70与190 keV的结石胆汁对比之间存在显著差异（p < 0.0001）。结论低keV虚拟单色成像增加了非钙化胆结石的显着性，提高了其可检测性。
PurposeTo determine whether virtual monochromatic imaging (VMI) increases detectability of noncalcified gallstones on dual-energy CT (DECT) compared with conventional CT imaging.Materials and methodsThis retrospective IRB-approved, HIPAA-compliant study included consecutive patients who underwent DECT of the abdomen in the Emergency Department during a 30-month period (July 1, 2013-December 31, 2015), with a comparison US or MR within 1-year. 51 patients (36F, 15M; mean age 52 years) fulfilled the inclusion criteria. All DECT were acquired on a dual-source 128 × 2 slice scanner using either 80/Sn140 or 100/Sn140 kVp pairs. Source images at high and low kVp were used for DE post-processing with VMI. Within 3 mm reconstructed images, regions of interest of 0.5 cm2 were placed on noncalcified gallstones and bile to record hounsfield units (HU) at VMI energy levels ranging between 40 and 190 keV.ResultsNoncalcified gallstones uniformly demonstrated lowest HU at 40 keV and increase at higher keV; the HU of bile varied at higher keV. Few of the noncalcified stones are visible at 70 keV (simulating a conventional 120 kVp scan), with measured contrast (bile-stone HU difference) <10 HU in 78%, 10–20 HU in 20%, and >20 HU in 2%. Contrast was maximal at 40 keV, where 100% demonstrated >20 HU difference from surrounding bile, 75% >44 HU difference, and 50% >60 HU difference. A paired t test demonstrated a significant difference (p < 0.0001) between this stone-bile contrast at 40 vs. 70 keV and 70 vs. 190 keV.ConclusionLow keV virtual monochromatic imaging increased conspicuity of noncalcified gallstones, improving their detectability.
影响因子：
19.7
作者：
McCollough CH;Leng S;Yu L;Fletcher JG
通讯作者：
Fletcher JG
影响因子：
29.4
作者：
Wang, Helen H.;Portincasa, Piero;Wang, David Q. -H
通讯作者：
Wang, David Q. -H