Noninvasive imaging assessment of portal hypertension.

Noninvasive imaging assessment of portal hypertension.
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DOI:
10.1007/s00261-020-02729-7
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发表时间:
2020-11
影响因子:
2.4
通讯作者:
Taouli, Bachir
Taouli, Bachir
中科院分区:
医学3区
文献类型:
--
作者:
Kennedy, Paul;Bane, Octavia;Hectors, Stefanie J.;Fischman, Aaron;Schiano, Thomas;Lewis, Sara;Taouli, Bachir

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门静脉高压症(portal hypertension,PH)是慢性肝病(chronic liver disease,CLD)和肝硬化的一系列并发症,临床表现包括腹水、胃食管静脉曲张、脾肿大、脾功能亢进、肝性胸水、肝肾综合征、肝硬化综合征和门静脉高压症。PH的严重程度不同,通过有创肝静脉压力梯度测量(HVPG)进行诊断,HVPG被认为是参考标准。PH的准确诊断和严重程度的评估是高度相关的,因为具有临床意义的门静脉高压症(CSPH)患者发生急性静脉曲张出血和死亡的风险较高。在这篇综述中,我们讨论了目前和即将到来的非侵入性成像方法的诊断和评估的严重程度。
Portal hypertension (PH) is a spectrum of complications of chronic liver disease (CLD) and cirrhosis, with manifestations including ascites, gastroesophageal varices, splenomegaly, hypersplenism, hepatic hydrothorax, hepatorenal syndrome, hepatopulmonary syndrome and portopulmonary hypertension. PH can vary in severity and is diagnosed via invasive hepatic venous pressure gradient measurement (HVPG), which is considered the reference standard. Accurate diagnosis of PH and assessment of severity are highly relevant as patients with clinically significant portal hypertension (CSPH) are at higher risk for developing acute variceal bleeding and mortality. In this review we discuss current and upcoming noninvasive imaging methods for diagnosis and assessment of severity of PH.
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