The role of multimorbidity and socio-economic characteristics as potential risk factors for Long Covid: evidence from the multilevel analysis of the Survey of Health, Ageing and Retirement in Europe's corona surveys (2020-2021).
The role of multimorbidity and socio-economic characteristics as potential risk factors for Long Covid: evidence from the multilevel analysis of the Survey of Health, Ageing and Retirement in Europe's corona surveys (2020-2021).
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DOI：
10.1093/ageing/afad225
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发表时间：
2023-12-01
期刊：
影响因子：
6.7
通讯作者：
中科院分区：
文献类型：
--
作者：
很大一部分人在新型冠状病毒肺炎急性期后继续出现持续症状。然而，缺乏基于人群的长期新冠病毒风险因素研究。估计感染新型冠状病毒（COVID-19）的欧洲中老年人群中长期冠状病毒（COVID-19）的患病率，并评估多发病率和社会经济特征作为长期冠状病毒（COVID-19）潜在风险因素的作用。这项基于人群的纵向前瞻性研究涉及来自27个国家的50岁及以上受访者（n = 4，004），他们参加了2020年和2021年欧洲健康，老龄化和退休调查（SHARE），特别是Corona调查。通过多水平（随机截距）栅栏负二项模型进行分析。总体而言，71.6%（95%置信区间= 70.2-73.0%）的新冠病毒感染者在感染后12个月内至少有一种长期新冠病毒症状，平均3.06（标准差= 1.88）个症状。在长期新冠肺炎的患病率和症状数量方面存在显著的跨国差异。高等教育和男性与长期新冠病毒的风险较低相关，而就业与长期新冠病毒的风险较高相关。多发性硬化症与更多的症状相关，而年龄较大与较少的症状相关。我们的研究结果为欧洲长期新型冠状病毒的巨大负担提供了证据。感染新型冠状病毒的个人可能需要长期支持或进一步的医疗干预，给国家卫生保健系统带来额外压力。
A substantial proportion of individuals continue experiencing persistent symptoms following the acute stage of their Covid-19 illness. However, there is a shortage of population-based studies on Long Covid risk factors. To estimate the prevalence of Long Covid in the population of middle-aged and older Europeans having contracted Covid-19 and to assess the role of multimorbidity and socio-economic characteristics as potential risk factors of Long Covid. A population-based longitudinal prospective study involving a sample of respondents 50 years and older (n = 4,004) from 27 countries who participated in the 2020 and 2021 Survey of Health, Ageing and Retirement in Europe (SHARE), in particular the Corona Surveys. Analyses were conducted by a multilevel (random intercept) hurdle negative binomial model. Overall, 71.6% (95% confidence interval = 70.2–73.0%) of the individuals who contracted Covid-19 had at least one symptom of Long Covid up to 12 months after the infection, with an average of 3.06 (standard deviation = 1.88) symptoms. There were significant cross-country differences in the prevalence of Long Covid and number of symptoms. Higher education and being a man were associated with a lower risk of Long Covid, whilst being employed was associated with a higher risk of having Long Covid. Multimorbidity was associated with a higher number of symptoms and older age was associated with a lower number of symptoms. Our results provide evidence on the substantial burden of Long Covid in Europe. Individuals who contracted Covid-19 may require long-term support or further medical intervention, putting additional pressure on national health care systems.
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DOI：
10.3390/ijerph18031256
发表时间：
2021-01-30
影响因子：
--
作者：
Marí-Dell'Olmo M;Gotsens M;Pasarín MI;Rodríguez-Sanz M;Artazcoz L;Garcia de Olalla P;Rius C;Borrell C
通讯作者：
Borrell C
在普通人群中自我报告的长期互联：社会人口统计学和健康在跨国样本中相关。
影响因子：
3.2
作者：
Bonsaksen, Tore;Leung, Janni;Price, Daicia;Ruffolo, Mary;Lamph, Gary;Kabelenga, Isaac;Thygesen, Hilde;Geirdal, Amy Ostertun
通讯作者：
Geirdal, Amy Ostertun
影响因子：
2.1
作者：
GROGGER, JT;CARSON, RT
通讯作者：
CARSON, RT
DOI：
10.1126/science.abg5298
发表时间：
2021-05-28
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Mena GE;Martinez PP;Mahmud AS;Marquet PA;Buckee CO;Santillana M
通讯作者：
Santillana M
影响因子：
105.7
作者：
Peter, Raphael S.;Nieters, Alexandra;Krausslich, Hans-Georg;Brockmann, Stefan O.;Gopel, Siri;Kindle, Gerhard;Merle, Uta;Steinacker, Jurgen M.;Rothenbacher, Dietrich;Kern, Winfried, V
通讯作者：
Kern, Winfried, V