Population clocks: motor timing with neural dynamics.

Population clocks: motor timing with neural dynamics.
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DOI:
10.1016/j.tics.2010.09.002
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发表时间:
2010-12
影响因子:
19.9
通讯作者:
Laje, Rodrigo
Laje, Rodrigo
中科院分区:
心理学1区
文献类型:
--
作者:
Buonomano, Dean V.;Laje, Rodrigo

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要理解感觉和运动过程,就需要阐明大脑报时的机制。悬而未决的问题涉及计时是否依赖于专用机制或内在机制,以及不同规模和方式的计时是否以不同的机制为基础。尽管实验和理论研究支持神经回路本质上能够在短尺度上进行感觉计时的概念,但很少有人提出运动计时的一般模型。对于一类模型,即种群时钟,有人提出,时间是以一群神经元活动的时变模式来编码的。我们认为,种群时钟产生于反复连接的网络的内部动态,在生物学上是现实的,并解释了运动计时的许多方面。
An understanding of sensory and motor processing will require elucidation of the mechanisms by which the brain tells time. Open questions relate to whether timing relies on dedicated or intrinsic mechanisms and whether distinct mechanisms underlie timing across scales and modalities. Although experimental and theoretical studies support the notion that neural circuits are intrinsically capable of sensory timing on short scales, few general models of motor timing have been proposed. For one class of models, population clocks, it is proposed that time is encoded in the time-varying patterns of activity of a population of neurons. We argue that population clocks emerge from the internal dynamics of recurrently connected networks, are biologically realistic and account for many aspects of motor timing.
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