Sensory-motor interactions for vocal pitch monitoring in non-primary human auditory cortex.
Sensory-motor interactions for vocal pitch monitoring in non-primary human auditory cortex.
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DOI：
10.1371/journal.pone.0060783
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Howard MA 3rd
中科院分区：
文献类型：
--
作者：
Greenlee JD;Behroozmand R;Larson CR;Jackson AW;Chen F;Hansen DR;Oya H;Kawasaki H;Howard MA 3rd
自我发声过程中听觉反馈的神经机制还不清楚。一种用于研究听觉反馈作用的技术涉及改变说话者接收到的反馈的音高，称为音高变换反馈。本研究采用音高变换自发声和回放的实验范式，探讨了声-音相互作用的神经机制。高分辨率皮层电图（ECoG）信号直接从10名人类受试者的听觉皮层记录下来，同时他们发声并在语音听觉反馈（说话任务）中接受短暂的向下（-100美分）音高扰动。当受试者被动地听他们自己的音高变化的声音回放时，ECoG也被记录下来。反馈音高扰动引起的平均诱发电位（AEP）和事件相关频带功率（ERBP）的反应，主要是在高伽马（70-150 Hz）的范围内，在非初级听觉皮层的上级颞回（STG）的焦点区域。AEP和高伽玛反应都调制说话相比，播放在一个子集的STG接触。从这些接触中，大多数显示出显着增强的高伽玛功率和AEP反应在说话，而其余的接触显示衰减的反应幅度。说话引起的增强效应表明，从事声乐运动系统可以调节听觉皮层处理的自产声音的方式，以增加神经的灵敏度反馈音高错误检测。这是可能的机制，如传出副本可能涉及在这个过程中，和调制的AEP和高伽玛反应意味着这种调制效应可能会影响不同的皮质发电机内独特的功能网络，驱动语音的生产和控制。
The neural mechanisms underlying processing of auditory feedback during self-vocalization are poorly understood. One technique used to study the role of auditory feedback involves shifting the pitch of the feedback that a speaker receives, known as pitch-shifted feedback. We utilized a pitch shift self-vocalization and playback paradigm to investigate the underlying neural mechanisms of audio-vocal interaction. High-resolution electrocorticography (ECoG) signals were recorded directly from auditory cortex of 10 human subjects while they vocalized and received brief downward (−100 cents) pitch perturbations in their voice auditory feedback (speaking task). ECoG was also recorded when subjects passively listened to playback of their own pitch-shifted vocalizations. Feedback pitch perturbations elicited average evoked potential (AEP) and event-related band power (ERBP) responses, primarily in the high gamma (70–150 Hz) range, in focal areas of non-primary auditory cortex on superior temporal gyrus (STG). The AEPs and high gamma responses were both modulated by speaking compared with playback in a subset of STG contacts. From these contacts, a majority showed significant enhancement of high gamma power and AEP responses during speaking while the remaining contacts showed attenuated response amplitudes. The speaking-induced enhancement effect suggests that engaging the vocal motor system can modulate auditory cortical processing of self-produced sounds in such a way as to increase neural sensitivity for feedback pitch error detection. It is likely that mechanisms such as efference copies may be involved in this process, and modulation of AEP and high gamma responses imply that such modulatory effects may affect different cortical generators within distinctive functional networks that drive voice production and control.
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影响因子：
3.7
作者：
Coudé G;Ferrari PF;Rodà F;Maranesi M;Borelli E;Veroni V;Monti F;Rozzi S;Fogassi L
通讯作者：
Fogassi L
影响因子：
2.9
作者：
Behroozmand R;Korzyukov O;Larson CR
通讯作者：
Larson CR
影响因子：
2.4
作者：
Burnett, TA;Freedland, MB;Hain, TC
通讯作者：
Hain, TC
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
3.7
作者：
Eliades, SJ;Wang, XQ
通讯作者：
Wang, XQ