Through the lens of culture: quality of life among Latina breast cancer survivors.
Through the lens of culture: quality of life among Latina breast cancer survivors.
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DOI：
10.1007/s10549-012-2291-2
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发表时间：
2012-11
影响因子：
3.8
通讯作者：
Mandelblatt, Jeanne
中科院分区：
文献类型：
--
作者：
Graves, Kristi D.;Jensen, Roxanne E.;Canar, Janet;Perret-Gentil, Monique;Leventhal, Kara-Grace;Gonzalez, Florencia;Caicedo, Larisa;Jandorf, Lina;Kelly, Scott;Mandelblatt, Jeanne
拉丁裔癌症幸存者的生活质量低于高加索人，但我们对这一不断增长的人群中与生活质量相关的因素知之甚少。双语工作人员对264名拉丁裔乳腺癌幸存者的全国横断面样本进行了采访。使用癌症治疗功能评估-乳腺（FACT-B）测量生活质量。回归模型评估了文化，社会和医疗背景与整体生活质量及其子领域之间的关联。拉丁裔幸存者在诊断后1-5年，与其他已发表的非拉丁裔幸存者报告相比，报告的平均生活质量评分较低（M=105; FACT-B的SD=19.4）。基于文化的乳腺癌相关的耻辱感和羞耻感始终与整体生活质量较低和每个生活质量领域的幸福感较低有关。社会和医疗背景因素与生活质量独立相关;文化、社会和医疗背景因素共同解释了整体生活质量解释模型方差的62%（调整后R2=0.53，P<.001）。在生活质量子领域中也观察到了类似的关系，其中文化，社会和医疗背景变量独立地对每个最终模型的总体方差做出了贡献：身体健康（调整后的R2=0.23，P <.001），社会幸福感（调整后的R2=0.51，P<.001），情绪健康（调整后的R2=0.28，P<.001），功能健康（调整后的R2=0.41，P<.001）和额外的乳房问题（调整后的R2=0.40，P<.001）。努力改善拉丁美洲人的生存经验，应考虑文化，社会和医疗背景因素，以缩小拉丁美洲人和其他幸存者之间现有的生活质量差距。
Latinas have lower quality of life than Caucasian cancer survivors but we know little about factors associated with quality of life in this growing population. Bilingual staff conducted interviews with a national cross-sectional sample of 264 Latina breast cancer survivors. Quality of life was measured using the Functional Assessment of Cancer Therapy-Breast (FACT-B). Regression models evaluated associations between culture, social and medical context and overall quality of life and its subdomains. Latina survivors were 1-5 years post-diagnosis and reported a lower mean quality of life score compared to other published reports of non-Latina survivors (M=105; SD=19.4 on the FACT-B). Culturally-based feelings of breast cancer-related stigma and shame were consistently related to lower overall quality of life and lower well-being in each quality of life domain. Social and medical contextual factors were independently related to quality of life; together cultural, social and medical context factors uniquely accounted for 62% of the explained model variance of overall quality of life (Adjusted R2=0.53, P<.001). Similar relationships were seen for quality of life subdomains in which cultural, social and medical contextual variables independently contributed to the overall variance of each final model: physical well-being (Adjusted R2=0.23, P <.001), social well-being (Adjusted R2=0.51, P<.001), emotional well-being (Adjusted R2=0.28, P<.001), functional well-being (Adjusted R2=0.41, P<.001) and additional breast concerns (Adjusted R2=0.40, P<.001). Efforts to improve Latinas’ survivorship experiences should consider cultural, social and medical contextual factors to close existing quality of life gaps between Latinas and other survivors.
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