Randomized controlled trial to assess the short-term effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care (iQuit in practice).
Randomized controlled trial to assess the short-term effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care (iQuit in practice).
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DOI：
10.1111/add.12556
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发表时间：
2014-07
期刊：
影响因子：
--
通讯作者：
Sutton S
中科院分区：
文献类型：
--
作者：
Naughton F;Jamison J;Boase S;Sloan M;Gilbert H;Prevost AT;Mason D;Smith S;Brimicombe J;Evans R;Sutton S
评估戒烟干预（iQuit系统）的短期有效性、可行性和可接受性，该系统包括量身定制的印刷品和短信服务（SMS）短信自助，作为初级保健戒烟支持的辅助手段，为最终试验的设计提供信息。一项比较常规护理（对照）与常规护理加iQuit系统（干预）的分层双平行组随机对照试验，由对分配顺序不知情的初级保健护士/医疗保健助理提供。英国英格兰的32个全科医生（GP）手术。共有602名从当地GP手术开始戒烟支持的吸烟者被随机分组（对照组n = 303，干预组n = 299）。主要结局是8周随访时自我报告的2周时点戒烟率。在戒烟日期后4周、8周和6个月随访时收集继发性吸烟结果以及可行性和可接受性测量。主要结局[对照组40.3%，iQuit组45.2%;比值比（OR）= 1.22，95%置信区间（CI）= 0.88-1.69]或次要短期吸烟结局无显著组间差异。iQuit组6个月的长期戒烟率显著较高（对照组8.9%，iQuit组15.1%; OR = 1.81，95% CI = 1.09-3.01）。iQuit支持平均需要7.7分钟（标准差= 4.0），18.9%（95% CI = 14.8-23.7%）的干预参与者在计划期间停止了短信支持。在初级保健中，与常规戒烟支持一起提供量身定制的印刷和短信自助服务不会显著增加短期戒烟率，但与单独的常规戒烟支持相比，可能会增加长期戒烟率，并证明其可行性和可接受性。
To estimate the short-term effectiveness, feasibility and acceptability of a smoking cessation intervention (the iQuit system) that consists of tailored printed and Short Message Service (SMS) text message self-help delivered as an adjunct to cessation support in primary care to inform the design of a definitive trial. A stratified two parallel-group randomized controlled trial comparing usual care (control) with usual care plus the iQuit system (intervention), delivered by primary care nurses/healthcare assistants who were blinded to the allocation sequence. Thirty-two general practice (GP) surgeries in England, UK. A total of 602 smokers initiating smoking cessation support from their local GP surgery were randomized (control n = 303, intervention n = 299). Primary outcome was self-reported 2-week point prevalence abstinence at 8 weeks follow-up. Secondary smoking outcomes and feasibility and acceptability measures were collected at 4 weeks after quit date, 8 weeks and 6 months follow-up. There were no significant between-group differences in the primary outcome [control 40.3%, iQuit 45.2%; odds ratio (OR) = 1.22, 95% confidence interval (CI) = 0.88–1.69] or in secondary short-term smoking outcomes. Six-month prolonged abstinence was significantly higher in the iQuit arm (control 8.9%, iQuit 15.1%; OR = 1.81, 95% CI = 1.09–3.01). iQuit support took on average 7.7 minutes (standard deviation = 4.0) to deliver and 18.9% (95% CI = 14.8–23.7%) of intervention participants discontinued the text message support during the programme. Tailored printed and text message self-help delivered alongside routine smoking cessation support in primary care does not significantly increase short-term abstinence, but may increase long-term abstinence and demonstrated feasibility and acceptability compared with routine cessation support alone.
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