Risk indicators for HIV-associated jointly occurring oral candidiasis and oral hairy leukoplakia.
Risk indicators for HIV-associated jointly occurring oral candidiasis and oral hairy leukoplakia.
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HIV 相关联合发生的口腔念珠菌病和口腔毛状白斑的风险指标。
DOI：
10.1089/apc.2007.0033
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发表时间：
2007
影响因子：
4.9
通讯作者：
Patton,LaurenL
中科院分区：
文献类型：
--
作者：
Chattopadhyay,Amit;Patton,LaurenL
Joint occurrence of two or more diseases may impact their transmission, clinical presentation, management approaches, and treatment efficacy. Although oral candidiasis (OC) and oral hairy leukoplakia (OHL) are the most commonly occurring opportunistic oral diseases of HIV-infected patients, literature describing their joint occurrence is sparse. The purpose of this project was to develop an explanatory multivariable model for joint occurrence of OC and OHL (OC-OHL). This cross-sectional study examined 631 adult dentate HIV-1 seropositive persons for OC and OHL from 1995–2000 at the University of North Carolina Hospitals in Chapel Hill, NC. Data collected from medical record review, interviews and clinical examinations were analyzed usingχ2tests,titests, and nonparametric tests. Multivariable proportional odds models were developed, using the likelihood ratio test and adjusting for several demographic, behavioral, and biological factors. Thirteen percent of participants had OC only; 12.8% had OHL only; 4.6% had OC-OHL; whereas 69.7% had neither. Occurrence of OC-OHL was independently associated with CD4+counts less than 200 cells per microliter (adjusted odds ratio [OR] (95% confidence interval {CI}) = 13.4 (6.6, 27.2) and CD4+counts 200–499 cells per microliter (OR = 3.9 [1.9, 8.1]); current smokers (OR = 2.3 [1.4, 3.8]); and whites (OR = 1.7 [1.1, 2.5]). Combination antiretroviral therapy was protective (OR = 0.5 [0.3, 0.9]). In an HIV-1–infected population, lower CD4+cell counts and smoking were important independent risk indicators for joint occurrence of OC and OHL.
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使用 sas® 系统进行分类数据分析，第二版
DOI：
--
发表时间：
2000
期刊：
影响因子：
--
作者：
M. Stokes;C. S. Davis;G. Koch
通讯作者：
G. Koch
优先考虑艾滋病毒初级保健：合并症、毒性和人口统计学。
DOI：
--
发表时间：
2006
期刊：
Topics in HIV medicine : a publication of the International AIDS Society, USA
影响因子：
--
作者：
A. Justice
通讯作者：
A. Justice
DOI：
10.1016/s1079-2104(00)70092-8
发表时间：
2000-03-01
期刊：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
影响因子：
--
作者：
Patton, LL;McKaig, R;Eron, JE
通讯作者：
Eron, JE
口腔病变及其对 HIV 疾病进展的预测价值的前瞻性研究。
DOI：
10.1111/j.1601-0825.1997.tb00032.x
发表时间：
1997
期刊：
Oral diseases.
影响因子：
--
作者：
Begg,MD;Lamster,IB;Panageas,KS;Mitchell-Lewis,D;Phelan,JA;Grbic,JT
通讯作者：
Grbic,JT
影响因子：
3.8
作者：
Eyeson, JD;Warnakulasuriya, KAAS;Johnson, NW
通讯作者：
Johnson, NW