Right ventricular function in pulmonary hypertension due to left heart disease by two-dimensional speckle tracking and real time three-dimensional echocardiography
Right ventricular function in pulmonary hypertension due to left heart disease by two-dimensional speckle tracking and real time three-dimensional echocardiography
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二维散斑追踪和实时三维超声心动图对左心病肺动脉高压患者右心室功能的影响
DOI：
10.1080/ac.71.4.3159702
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发表时间：
2016-08
影响因子：
1.6
通讯作者：
Ren Jianli
中科院分区：
文献类型：
--
作者：
Zhang Lan;Zhang Ping;Qi Hongbo;Wang Zhigang;Luo Tiantian;Lu Min;Ran Haitao;Cao Chiying;Ren Jianli
目的应用二维斑点追踪超声心动图（2D-STE）和实时三维超声心动图（RT-3DE）评价左心肺动脉高压（LHD-PH）患者右室功能，并与常规超声心动图比较。根据肺血管阻力将患者分为被动性PH组和反应性PH组。常规超声心动图测量右室面积变化分数（FAC）、心肌工作指数（MPI）和收缩期速度（S '）。应用二维超声心动图测量右室游离壁基底段（LSbas）、中段（LSmid）和心尖段（LSapi）的纵向收缩期峰值应变（LS），计算整体游离壁LS（LSfw）。采用RT-3DE测定右室舒张末期容积（EDV）、收缩末期容积（ESV）、射血分数（EF）和每搏输出量（SV）。结果与被动性肺高压组比较，反应性肺高压组LSbas、LSfw、EF、FAC、S'均降低（均P < 0.05）。而对照组与被动PH组之间无显著性差异（均P> 0.05）。EDV、ESV、MPI随病程进展逐渐增高（均P < 0.05）。Logistic回归分析显示，LSbas和EF与反应性PH独立相关，ROC曲线分析显示，LSbas和EF对反应性PH的敏感性分别为83%和86%，特异性分别为89%和81%。结论右室呈渐进性扩张，收缩功能恶化晚于右室。2D应变和3D容积评估能够比常规超声心动图更好地识别反应性PH。
Objective The aim of this study was to assess right ventricular (RV) function in pulmonary hypertension due to left heart disease (LHD-PH) by two-dimensional speckle tracking echocardiography (2D-STE) and real-time three-dimensional echocardiography (RT-3DE) and to compare them with conventional echocardiography in identifying reactive PH. Subjects and methods The study consisted of 40 controls and 65 patients with LHD-PH. According to pulmonary vascular resistance, patients were divided into a passive PH and a reactive PH group. RV fractional area change (FAC), myocardial performance index (MPI) and systolic velocity (S’) were acquired by conventional echocardiography. Longitudinal peak systolic strain (LS) was measured at the basal (LSbas), middle (LSmid) and apical (LSapi) segments of RV free wall by 2D-STE, and global free wall LS (LSfw) was calculated. RV end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF) and stroke volume (SV) were acquired using RT-3DE. Results Compared with the passive PH group, LSbas, LSfw, EF, FAC and S’ decreased in reactive PH group (all P < 0.05). However, they showed no significant differences between controls and the passive PH group (all P> 0.05). EDV, ESV and MPI increased gradually as the disease progressed (all P < 0.05). By logistic regression analysis, only LSbas and EF were independently associated with reactive PH. By ROC analysis, they were indicative of reactive PH with sensitivity of 83% and 86%, and specificity of 89% and 81%. Conclusions RV presented gradual dilatation with deteriorated systolic function that occurred late. 2D strain and3D volumetric assessments were able to identity reactive PH better than conventional echocardiography.
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DOI：
10.1161/circimaging.112.976654
发表时间：
2012-11
期刊：
Circulation. Cardiovascular imaging
影响因子：
--
作者：
Opotowsky AR;Ojeda J;Rogers F;Prasanna V;Clair M;Moko L;Vaidya A;Afilalo J;Forfia PR
通讯作者：
Forfia PR
影响因子：
37.8
作者：
Rain, Silvia;Handoko, M. Louis;de Man, Frances S.
通讯作者：
de Man, Frances S.
影响因子：
1.6
作者：
Ajami, Gholam Hossein;Cheriki, Sirous;Soltani, Manoucher
通讯作者：
Soltani, Manoucher
影响因子：
1.5
作者：
K. Shiino;Kunihiko Sugimoto;A. Yamada;K. Takada;H. Kawai;K. Sugimoto;Hiroshi Takahashi;Y. Takagi;M. Iwase;Y. Ozaki
通讯作者：
K. Shiino;Kunihiko Sugimoto;A. Yamada;K. Takada;H. Kawai;K. Sugimoto;Hiroshi Takahashi;Y. Takagi;M. Iwase;Y. Ozaki
影响因子：
39.3
作者：
O. Bech-Hanssen;B. Fadel;W. Al-Habeeb;J. Al-Buraiki;N. Selimovic
通讯作者：
O. Bech-Hanssen;B. Fadel;W. Al-Habeeb;J. Al-Buraiki;N. Selimovic