MRI driven magnetic microswimmers.

MRI driven magnetic microswimmers.
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DOI:
10.1007/s10544-011-9594-7
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发表时间:
2012-02
影响因子:
2.8
通讯作者:
Hata, Nobuhiko
Hata, Nobuhiko
中科院分区:
工程技术3区
文献类型:
--
作者:
Kosa, Gabor;Jakab, Peter;Szekely, Gabor;Hata, Nobuhiko

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胶囊内镜是一种很有前途的诊断消化系统疾病的技术。在这里,我们设计并表征了一个微型游泳机制,该机制使用MRI的磁场为胶囊提供推进和无线供电。我们的方法使用MRI中固有的静态和射频(RF)磁场来产生推进力。我们的研究重点是不同的游泳尾巴和实验估计的参数,影响其大小的推进力的评估。我们已经发现,当由提供0.85 mW功率的20 Hz信号驱动并且尾部位于3 T MRI扫描仪的均匀场中时,大约20 mm长、5 mm宽的游泳尾部能够在水中产生0.21 mN的推进力。分析了游动机构与扫描成像的并行工作。我们描述了由推进系统引起的伪影的大小。我们表明,而磁性微游泳推进胶囊内窥镜,操作员可以定位胶囊的介入场景的图像上,而不会被掩盖的显着文物。虽然这种游动方法不能有利地缩小规模,但MRI的高磁场允许每秒几毫米量级的自推进速度,并且可以在胃中推进内窥镜胶囊。
Capsule endoscopy is a promising technique for diagnosing diseases in the digestive system. Here we design and characterize a miniature swimming mechanism that uses the magnetic fields of the MRI for both propulsion and wireless powering of the capsule. Our method uses both the static and the radio frequency (RF) magnetic fields inherently available in MRI to generate a propulsive force. Our study focuses on the evaluation of the propulsive force for different swimming tails and experimental estimation of the parameters that influence its magnitude. We have found that an approximately 20 mm long, 5 mm wide swimming tail is capable of producing 0.21 mN propulsive force in water when driven by a 20 Hz signal providing 0.85 mW power and the tail located within the homogeneous field of a 3 T MRI scanner. We also analyze the parallel operation of the swimming mechanism and the scanner imaging. We characterize the size of artifacts caused by the propulsion system. We show that while the magnetic micro swimmer is propelling the capsule endoscope, the operator can locate the capsule on the image of an interventional scene without being obscured by significant artifacts. Although this swimming method does not scale down favorably, the high magnetic field of the MRI allows self propulsion speed on the order of several millimeter per second and can propel an endoscopic capsule in the stomach.
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影响因子: 2.1
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DOI: 10.1103/physreve.75.041916
发表时间: 2007-04-01
期刊: PHYSICAL REVIEW E
影响因子: 2.4
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