Preoperative masked renal damage in Japanese patients with primary aldosteronism: Identification of predictors for chronic kidney disease manifested after adrenalectomy

Preoperative masked renal damage in Japanese patients with primary aldosteronism: Identification of predictors for chronic kidney disease manifested after adrenalectomy
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日本原发性醛固酮增多症患者术前隐匿性肾损伤:肾上腺切除术后慢性肾病预测因素的鉴定

DOI:
10.1111/iju.12029
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发表时间:
2013
影响因子:
2.6
通讯作者:
T. Ichikawa
T. Ichikawa
中科院分区:
医学3区
文献类型:
--
作者:
T. Utsumi;K. Kawamura;T. Imamoto;Hidekazu Nagano;Tomoaki Tanaka;N. Kamiya;N. Nihei;Y. Naya;Hiroyoshi Suzuki;T. Ichikawa

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在肾上腺切除术前,很难正确解释原发性醛固酮增多症患者的肾功能,因为微小的肾脏损害往往被原发性醛固酮增多症所特有的肾小球高滤过掩盖。本研究的目的是研究原发性醛固酮增多症患者术后肾功能的变化,并确定非既往慢性肾脏疾病患者术后表现为慢性肾脏疾病的临床预测因素。
Correct interpretation of renal function in patients with primary aldosteronism is difficult before adrenalectomy, because subtle kidney impairment is often masked by glomerular hyperfiltration peculiar to primary aldosteronism. The aim of this study was to investigate postoperative changes in renal function for patients with primary aldosteronism and to identify clinical predictors of chronic kidney disease manifested postoperatively in the patients without pre‐existing chronic kidney disease.
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