How do meiotic chromosomes meet their homologous partners?: lessons from fission yeast
How do meiotic chromosomes meet their homologous partners?: lessons from fission yeast
复制标题
减数分裂染色体如何遇到它们的同源伴侣？：裂殖酵母的教训
作者：
A. Yamamoto;Y. Hiraoka
同源染色体配对是减数分裂过程中染色体正确分离和重组所必需的。一对同源染色体相互接触以建立配对的机制尚未完全了解。当在裂殖酵母裂殖酵母的减数分裂前期发生配对时，细胞核在细胞两极之间振荡，端粒保持聚集在移动的细胞核的前缘。这些减数分裂特异性活动产生端粒束染色体的运动。一些证据表明，这些运动通过对齐同源染色体和促进同源区域之间的接触来促进同源染色体配对。由于在广泛的真核生物中已经观察到端粒聚集和减数分裂前期的核或染色体运动，因此建议端粒介导的染色体运动是促进同源染色体配对的一般活动。BioEssays 23：526-533，2001年。John Wiley & Sons，Inc.
Homologous chromosome pairing is required for proper chromosome segregation and recombination during meiosis. The mechanism by which a pair of homologous chromosomes contact each other to establish pairing is not fully understood. When pairing occurs during meiotic prophase in the fission yeast, Schizosaccharomyces pombe, the nucleus oscillates between the cell poles and telomeres remain clustered at the leading edge of the moving nucleus. These meiosis‐specific activities produce movements of telomere‐bundled chromosomes. Several lines of evidence suggest that these movements facilitate homologous chromosome pairing by aligning homologous chromosomes and promoting contact between homologous regions. Since telomere clustering and nuclear or chromosome movements in meiotic prophase have been observed in a wide range of eukaryotic organisms, it is suggested that telomere‐mediated chromosome movements are general activities that facilitate homologous chromosome pairing. BioEssays 23:526–533, 2001. © 2001 John Wiley & Sons, Inc.
影响因子：
5.2
作者：
Malapit CA;Caldwell DR;Sassu N;Milbin S;Howell AR
通讯作者：
Howell AR
DOI：
10.1073/pnas.97.17.9537
发表时间：
2000-08-15
影响因子：
11.1
作者：
Goldman, ASH;Lichten, M
通讯作者：
Lichten, M
减数分裂染色体动力学依赖于裂殖酵母裂殖酵母的rec8( )、rec10( ) 和rec11( ) 基因。
影响因子：
3.3
作者：
Krawchuk,MD;DeVeaux,LC;Wahls,WP
通讯作者：
Wahls,WP