Pagliaccio, a member of the Eph family of receptor tyrosine kinase genes, has localized expression in a subset of neural crest and neural tissues in Xenopus laevis embryos
Pagliaccio, a member of the Eph family of receptor tyrosine kinase genes, has localized expression in a subset of neural crest and neural tissues in Xenopus laevis embryos
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Pagliaccio 是受体酪氨酸激酶基因 Eph 家族的成员,在非洲爪蟾胚胎的神经嵴和神经组织的子集中表达
DOI:
10.1016/0925-4773(94)90072-8
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发表时间:
1994
影响因子:
2.6
通讯作者:
T. Sargent
中科院分区:
文献类型:
--
作者:
R. Winning;T. Sargent
Cranial neural crest cells arise from neural folds in the embryonic head and differentiate to produce most of the cartilages and bones of the skull and the somatosensory ganglia of several cranial nerves, among other tissues. Since the molecular basis of the determination of these cells is poorly understood, we have begun a search for molecules involved in signal transduction in cranial neural crest. From aXenopus laeviscranial neural crest cDNA bank, we have cloned a cDNA encoding a putative receptor tyrosine kinase, which we callPagliaccio(Pag).PagRNA is present transiently in visceral arch 3, probably representing neural crest cells in this tissue.Pagis also expressed in the forebrain, rhombomeres r3 and r5 of the hindbrain and in the pronephros. Based on this localized expression, we propose thatPagmay play a role in the differentiation of cranial neural crest and other tissues.
DOI:
10.1242/dev.111.2.635
发表时间:
1991
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Stocker,KM;Sherman,L;Rees,S;Ciment,G
通讯作者:
Ciment,G
DOI:
10.1002/dvg.1020140305
发表时间:
1993
期刊:
Developmental genetics
影响因子:
--
作者:
Jones,SD;Ho,L;Smith,JC;Yordan,C;Stiles,CD;Mercola,M
通讯作者:
Mercola,M
DOI:
10.1242/dev.118.3.691
发表时间:
1993
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Sechrist,J;Serbedzija,GN;Scherson,T;Fraser,SE;Bronner-Fraser,M
通讯作者:
Bronner-Fraser,M