The economic burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).

The economic burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).
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DOI:
10.1111/j.1469-0691.2012.03914.x
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发表时间:
2013-06
期刊:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子:
--
通讯作者:
Daum RS
Daum RS
中科院分区:
其他
文献类型:
--
作者:
Lee BY;Singh A;David MZ;Bartsch SM;Slayton RB;Huang SS;Zimmer SM;Potter MA;Macal CM;Lauderdale DS;Miller LG;Daum RS

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社区相关耐甲氧西林金黄色葡萄球菌 (CA-MRSA) 的经济影响仍不清楚。我们开发了一个经济模拟模型,从社会和第三方付款人的角度量化与 CA-MRSA 感染相关的成本。单个 CA-MRSA 病例的费用由第三方付款人 2,277 美元至 3,200 美元,社会费用为 7,070 美元至 20,489 美元,具体费用取决于患者年龄。在美国 (US),CA-MRSA 每年给第三方支付者带来 4.78 亿至 22 亿美元的负担,给社会带来 14 亿至 138 亿美元的负担,具体取决于 CA-MRSA 的定义和发生率。美国监狱系统和陆军每年的总费用可能分别为 7 – 1100 万美元(6 – 1000 万美元直接医疗费用)和 15 – 3600 万美元(14 – 3200 万美元)。住院率和死亡率是重要的成本驱动因素。 CA-MRSA 给第三方支付者和社会带来了巨大的经济负担,而 CA-MRSA 造成的生产力损失是社会总经济负担的主要来源。虽然减少传播和感染发生率会降低成本,但即使传播继续保持目前的水平,在 CA-MRSA 感染进展之前及早识别和适当治疗也可以节省大量成本。
The economic impact of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) remains unclear. We developed an economic simulation model to quantify the costs associated with CA-MRSA infection from the societal and third-party payer perspectives. A single CA-MRSA case costs third-party payers $2,277 – $3,200 and society $7,070 – $20,489, depending on patient age. In the United States (US), CA-MRSA imposes an annual burden of $478 million - 2.2 billion on third-party payers and $1.4 billion - 13.8 billion on society, depending on the CA-MRSA definitions and incidences. The US jail system and Army may be experiencing annual total costs of $7 – 11 million ($6 – 10 million direct medical costs) and $15 – 36 million ($14 – 32 million), respectively. Hospitalization rates and mortality are important cost drivers. CA-MRSA confers a substantial economic burden to third-party payers and society, with CA-MRSA-attributable productivity losses being major contributors to the total societal economic burden. Although decreasing transmission and infection incidence would decrease costs, even if transmission were to continue at present levels, early identification and appropriate treatment of CA-MRSA infections before they progress could save considerable costs.
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