Adipokines and Gut Hormones in End-Stage Renal Disease
Adipokines and Gut Hormones in End-Stage Renal Disease
复制标题
终末期肾病中的脂肪因子和肠道激素
DOI:
10.1177/089686080702702s51
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发表时间:
2007
影响因子:
2.8
通讯作者:
W. Cheung
中科院分区:
文献类型:
--
作者:
R. Mak;W. Cheung
Cachexia is common in end-stage renal disease (ESRD) patients, and it is an important risk factor for poor quality of life and increased mortality and morbidity. Chronic inflammation is an important cause of cachexia in ESRD patients. In the present review, we examine recent evidence suggesting that adipokines or adipocytokines such as leptin, adiponectin, resistin, tumor necrosis factor α, interleukin-6, and interleukin-1β may play important roles in uremic cachexia. We also review the physiology and the potential roles of gut hormones, including ghrelin, peptide YY, and cholecystokinin in ESRD. Understanding the molecular pathophysiology of these novel hormones in ESRD may lead to novel therapeutic strategies.
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影响因子:
15.9
作者:
Cheung, W;Yu, PX;Mak, RH
通讯作者:
Mak, RH
影响因子:
4.4
作者:
Moran, TH
通讯作者:
Moran, TH
DOI:
10.1152/ajpgi.1985.248.1.g118
发表时间:
1985
期刊:
The American journal of physiology
影响因子:
--
作者:
Pappas,TN;Debas,HT;Goto,Y;Taylor,IL
通讯作者:
Taylor,IL
影响因子:
7.7
作者:
Faulconbridge, LF;Cummings, DE;Grill, HJ
通讯作者:
Grill, HJ