Impact of multimorbidity on disability and quality of life in the Spanish older population.

Impact of multimorbidity on disability and quality of life in the Spanish older population.
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多种疾病对西班牙老年人口残疾和生活质量的影响。

DOI:
10.1371/journal.pone.0111498
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Haro JM
Haro JM
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Garin N;Olaya B;Moneta MV;Miret M;Lobo A;Ayuso-Mateos JL;Haro JM

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在发达国家,人口老龄化与慢性病的高患病率密切相关。在这种情况下,医疗保健政策的目标是在维持生活质量和功能能力的同时,经济有效地延长寿命。然而,仍有必要进一步了解慢性疾病如何影响这些健康方面。本文的目的是评估西班牙慢性身体和精神状况对生活质量和残疾的个人和综合影响,其次是显示性别趋势。横断面数据收集自COURAGE研究。共有3625名50岁以上的西班牙人参与了这项研究。进行了粗糙和调整的多元线性回归,以检测个体慢性病与残疾之间以及慢性病与生活质量之间的关联。使用单独的模型来评估疾病数量对相同变量的影响。对男性和女性进行了额外的类似回归。除高血压外,所有慢性疾病均与生活质量差和残疾相关。研究发现,抑郁、焦虑和中风对结果的影响最大。慢性疾病的数量与较低的生活质量[4+疾病的β值:−18.10(−20.95,−15.25)]和更大的残疾[4+疾病的β值:27.64(24.99,30.29)]相关。一般来说,妇女的多重发病率较高,生活质量和残疾情况较差。慢性疾病对西班牙老年人口的生活质量和残疾有很大影响,特别是在合并疾病的情况下。在制定以生活质量和残疾为重点的未来卫生政策时,应优先考虑多发病问题。进一步的研究将受益于扩大疾病选择范围。政策还应在某些情况下处理性别特质。
Population aging is closely related to high prevalence of chronic conditions in developed countries. In this context, health care policies aim to increase life span cost-effectively while maintaining quality of life and functional ability. There is still, however, a need for further understanding of how chronic conditions affect these health aspects. The aim of this paper is to assess the individual and combined impact of chronic physical and mental conditions on quality of life and disability in Spain, and secondly to show gender trends. Cross-sectional data were collected from the COURAGE study. A total of 3,625 participants over 50 years old from Spain were included. Crude and adjusted multiple linear regressions were conducted to detect associations between individual chronic conditions and disability, and between chronic conditions and quality of life. Separate models were used to assess the influence of the number of diseases on the same variables. Additional analogous regressions were performed for males and females. All chronic conditions except hypertension were statistically associated with poor results in quality of life and disability. Depression, anxiety and stroke were found to have the greatest impact on outcomes. The number of chronic conditions was associated with substantially lower quality of life [β for 4+ diseases: −18.10 (−20.95,−15.25)] and greater disability [β for 4+ diseases: 27.64 (24.99,30.29]. In general, women suffered from higher rates of multimorbidity and poorer results in quality of life and disability. Chronic conditions impact greatly on quality of life and disability in the older Spanish population, especially when co-occurring diseases are added. Multimorbidity considerations should be a priority in the development of future health policies focused on quality of life and disability. Further studies would benefit from an expanded selection of diseases. Policies should also deal with gender idiosyncrasy in certain cases.
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