Neurocognitive therapeutics: from concept to application in the treatment of negative attention bias.

Neurocognitive therapeutics: from concept to application in the treatment of negative attention bias.
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DOI:
10.1186/s13587-015-0016-y
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发表时间:
2015
期刊:
Biology of mood & anxiety disorders
影响因子:
--
通讯作者:
Turk-Browne NB
Turk-Browne NB
中科院分区:
其他
文献类型:
--
作者:
Schnyer DM;Beevers CG;deBettencourt MT;Sherman SM;Cohen JD;Norman KA;Turk-Browne NB

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神经影像学在精神疾病的直接治疗中的应用越来越受到人们的关注。在这里,我们提出了一个新的框架,这种治疗,神经认知疗法。神经认知疗法与先前方法的区别在于在实时反馈系统中使用精确的大脑解码技术,以适应在线治疗并根据个人需求定制反馈。我们报告了一个初步的可行性研究,使用这个框架来改变负性注意力偏差在少数患者经历重大的情绪症状。这些结果与神经认知疗法改善情绪症状和改变调节注意力控制的大脑网络的承诺一致。未来的工作应该集中在优化方法,验证其有效性,并扩大目标疾病的范围。
There is growing interest in the use of neuroimaging for the direct treatment of mental illness. Here, we present a new framework for such treatment, neurocognitive therapeutics. What distinguishes neurocognitive therapeutics from prior approaches is the use of precise brain-decoding techniques within a real-time feedback system, in order to adapt treatment online and tailor feedback to individuals’ needs. We report an initial feasibility study that uses this framework to alter negative attention bias in a small number of patients experiencing significant mood symptoms. The results are consistent with the promise of neurocognitive therapeutics to improve mood symptoms and alter brain networks mediating attentional control. Future work should focus on optimizing the approach, validating its effectiveness, and expanding the scope of targeted disorders.
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