Vitamin D and diabetes: let the sunshine in.
Vitamin D and diabetes: let the sunshine in.
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DOI：
10.1177/0145721708326764
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发表时间：
2008-11
期刊：
影响因子：
--
通讯作者：
Emanuele MA
中科院分区：
文献类型：
--
作者：
Penckofer S;Kouba J;Wallis DE;Emanuele MA
糖尿病是心血管疾病的主要原因。糖尿病患者早期心脏死亡的风险更大，如果他们在第一次心脏事件中幸存下来，则重复事件的风险更大。最近，低血清维生素 D 浓度与心脏事件风险增加有关。有证据表明，糖尿病患者的血清维生素 D 浓度较低。此外，有患糖尿病或代谢综合征风险的人血清维生素 D 浓度不足。本综述将评估与维生素 D 在糖尿病、代谢综合征和糖尿病并发症发生过程中的影响相关的证据。提供了针对维生素 D 及其对代谢结果的影响以及可能的作用机制的研究。最后，讨论了维生素 D 缺乏症的评估和建议的治疗方法。有效检测和治疗糖尿病患者或有糖尿病风险的患者维生素 D 浓度不足可能是一种简单且经济有效的治疗方法，可以改善他们的长期健康结果以及生活质量。
Diabetes is a leading cause of cardiovascular disease. Persons with diabetes are at greater risk for early cardiac mortality, and for repeat events if they survive their first cardiac event. Recently, low serum concentrations of vitamin D have been associated with increased risk for cardiac events. Evidence indicates that persons with diabetes have lower serum concentrations of vitamin D. In addition, persons at risk for diabetes or metabolic syndrome have inadequate serum concentrations of vitamin D. This review will assess the evidence relative to the impact of vitamin D in the development of diabetes, metabolic syndrome, and diabetes complications. Studies that address vitamin D and its impact on metabolic outcomes as well as possible mechanisms of action are provided. Finally, the assessment and suggested treatment for vitamin D deficiency is addressed. Effective detection and treatment of inadequate vitamin D concentrations in persons with diabetes or those at risk for diabetes may be an easy and cost-effective therapy which could improve their long-term health outcomes as well as their quality of life.
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影响因子：
16.2
作者：
Ford, ES;Ajani, UA;Liu, S
通讯作者：
Liu, S
DOI：
10.1016/j.jsbmb.2006.12.066
发表时间：
2007-03-01
影响因子：
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作者：
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影响因子：
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作者：
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