A prediction model of atrial fibrillation recurrence after first catheter ablation by a nomogram: HASBLP score.

A prediction model of atrial fibrillation recurrence after first catheter ablation by a nomogram: HASBLP score.
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DOI:
10.3389/fcvm.2022.934664
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发表时间:
2022
影响因子:
3.6
通讯作者:
Zhong, Jingquan
Zhong, Jingquan
中科院分区:
医学3区
文献类型:
--
作者:
Han, Wenqiang;Liu, Yan;Sha, Rina;Liu, Huiyu;Liu, Aihua;Maduray, Kellina;Ge, Junye;Ma, Chuanzhen;Zhong, Jingquan

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目前,导管消融是心房颤动(AF)患者心律控制的有效方法。然而,房颤复发是导管消融后不可避免的问题。为了识别容易复发的患者,我们开发了一个预测模型,使临床医生能够密切监测这些患者,并采用不同的个性化治疗方案对他们进行治疗。
At present, catheter ablation is an effective method for rhythm control in patients with atrial fibrillation (AF). However, AF recurrence is an inevitable problem after catheter ablation. To identify patients who are prone to relapse, we developed a predictive model that allows clinicians to closely monitor these patients and treat them with different personalized treatment plans. A total of 1,065 patients who underwent AF catheter ablation between January 2015 and December 2018 were consecutively included in this study, which examines the results of a 2-year follow-up. Patients with AF were divided into development cohort and validation cohort. Univariate and multivariate analyses were carried out on the potential risk factors. Specific risk factors were used to draw the nomogram according to the above results. Finally, we verified the performance of our model compared with CHADS2 and CHA2DS2-Vasc scores by receiver operating characteristic (ROC) curve and calibration curve and plotted the decision analysis curve (DAC). A total of 316 patients experienced AF recurrence. After univariate and multivariate analyses, AF history (H), age (A), snoring (S), body mass index (BMI) (B), anteroposterior diameter of left atrial (LA) (L), and persistent AF (P) were included in our prediction model. Our model showed a better performance compared with CHADS2 and CHA2DS2-Vasc scores, and the area under ROC curve (95%CI) was 0.7668 (0.7298–0.8037) vs. 0.6225 (0.5783–0.6666) and 0.6267 (0.5836–0.6717). We established a nomogram (HASBLP score) for predicting AF recurrence after the first catheter ablation at a 2-year follow-up, which can be used as a tool to guide future follow-up of patients. However, its usefulness needs further validation.
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