End‐to‐side neurorrhaphy
End‐to‐side neurorrhaphy
复制标题
端侧神经缝合术
DOI：
10.1002/micr.21736
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发表时间：
2002
期刊：
影响因子：
2.1
通讯作者：
K. Fischer
中科院分区：
文献类型：
--
作者：
Feng Zhang;K. Fischer
端侧神经缝合术是一种治疗没有可用近端神经残端的神经病变的可能策略，已进行了实验和临床研究。在端侧神经缝合术中，应考虑三个主要因素：1）诱导供体神经中的轴突侧支发芽; 2）侧支轴突穿透不同结膜层的能力，包括供体神经基底层的能力，以重新支配受体神经; 3）最终采用新运动单位的单个运动神经元的功能可塑性和行为重新调整。本文综述了以下研究和临床调查领域：动物模型、端侧神经缝合的轴突侧支发芽、神经外膜切开术和神经束膜切开术对轴突再生的影响、运动神经再支配和临床试验。© 2002 Wiley利斯公司显微外科22：122-127 2002
End‐to‐side neurorrhaphy, a possible strategy for treating nerve lesions without useable proximal nerve stumps, has been experimentally and clinically investigated. In end‐to‐side neurorrhaphy, three main elements should be considered: 1) the induction of axonal collateral sprouting in the donor nerve; 2) the ability of the collateral axons to pierce the different conjunctival layers, including the ability the donor nerve basal laminae, to reinnervate the recipient nerve; and 3) the functional plasticity and behavioral readjustment of single motoneurons that have eventually adopted new motor units. This article reviews the following areas of research and clinical investigation: animal models, axonal collateral sprouting from end‐to‐side neurorrhaphy, effect of epineurotomy and perineurotomy on axon regeneration, motor reinnervation, and clinical trials. © 2002 Wiley Liss, Inc. MICROSURGERY 22:122–127 2002
影响因子：
3.6
作者：
Kalliainen, LK;Cederna, PS;Kuzon, WM
通讯作者：
Kuzon, WM