Radiation-associated liver injury.

Radiation-associated liver injury.
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DOI:
10.1016/j.ijrobp.2009.06.092
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发表时间:
2010-03-01
影响因子:
7
通讯作者:
Ten Haken, Randall K.
Ten Haken, Randall K.
中科院分区:
医学1区
文献类型:
--
作者:
Pan, Charlie C.;Kavanagh, Brian D.;Dawson, Laura A.;Li, X. Allen;Das, Shiva K.;Miften, Moyed;Ten Haken, Randall K.

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肝脏是一个非常重要的器官,具有许多功能,包括胆汁的产生,摄入营养物质的代谢,许多废物的消除,糖原储存和血浆蛋白质合成。在上腹部、右下肺、食管远端肿瘤的放射治疗(RT)过程中,或在全腹部或全身RT过程中,肝脏经常受到偶然照射。本文描述了放射对肝脏的终点、时间过程和剂量-体积效应。
The liver is a critically important organ that has numerous functions including the production of bile, metabolism of ingested nutrients, elimination of many waste products, glycogen storage, and plasma protein synthesis. The liver is often incidentally irradiated during radiation therapy (RT) for tumors in the upper- abdomen, right lower lung, distal esophagus, or during whole abdomen or whole body RT. This article describes the endpoints, time-course, and dose-volume effect of radiation on the liver.
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