The impact of evacuation on the incidence of chronic kidney disease after the Great East Japan Earthquake: The Fukushima Health Management Survey.
The impact of evacuation on the incidence of chronic kidney disease after the Great East Japan Earthquake: The Fukushima Health Management Survey.
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DOI：
10.1007/s10157-017-1395-8
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发表时间：
2017-12
影响因子：
2.3
通讯作者：
Abe M
中科院分区：
文献类型：
--
作者：
Hayashi Y;Nagai M;Ohira T;Satoh H;Sakai A;Ohtsuru A;Hosoya M;Kawasaki Y;Suzuki H;Takahashi A;Sugiura Y;Shishido H;Takahashi H;Yasumura S;Kazama JJ;Hashimoto S;Kobashi G;Ozasa K;Abe M
由于2011年东日本大地震引发的核电站事故，约有14.6万人被迫长期疏散。已知灾难会在一段时间内诱发幸存者的高血压，但长期的灾难压力是否会影响慢性肾病（CKD）尚不清楚。我们进行了一项观察性队列研究，以阐明疏散应激对CKD发病率的影响。参与者是居住在福岛核电站附近社区的个人，年龄在40-74岁之间，截至2011年一般健康检查时没有CKD（非疏散人员：n = 9780，疏散人员：n = 4712）。我们使用2012年至2014年的一般年度健康检查数据随访新发CKD [估计肾小球滤过率（eGFR）<60 ml/min/1.73 m2或蛋白尿]。使用考克斯比例风险模型分析疏散与CKD发病率之间的关联。基线时参与者的平均年龄为65岁，46.7%为男性，基线eGFR为75.7 ml/min/1.73 m2。在平均2.46年的随访期内，非撤离者和撤离者的CKD发病率分别为80.8/1000和100.2/1000人年。在校正年龄、性别、肥胖、高血压、糖尿病、血脂异常、吸烟和基线eGFR后，排空是CKD发病率的重要风险因素[风险比（HR）：1.45; 95%置信区间（CI）1.35-1.56]。排空与eGFR <60 ml/min/1.73 m2的发生率显著相关（HR：1.48; 95% CI 1.37-1.60），但与蛋白尿的发生率无关（HR：1.21; 95% CI 0.93-1.56）。疏散是灾难后CKD发病率的一个危险因素。
About 146,000 people were forced into long-term evacuation due to the nuclear power plant accident caused by the Great East Japan Earthquake in 2011. Disaster is known to induce hypertension in survivors for a certain period, but it is unclear whether prolonged disaster stress influences chronic kidney disease (CKD). We conducted an observational cohort study to elucidate the effects of evacuation stress on CKD incidence. Participants were individuals living in communities near the Fukushima nuclear power plant, aged 40–74 years without CKD as of their 2011 general health checkup (non-evacuees: n = 9780, evacuees: n = 4712). We followed new-onset CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2 or proteinuria] using general annual health checkup data from 2012 to 2014. Association between evacuation and CKD incidence was analyzed using the Cox proportional hazard model. Mean age of the participants at baseline was 65 years, 46.7% were men, and baseline eGFR was 75.7 ml/min/1.73 m2. During the mean follow-up period of 2.46 years, CKD incidence rate was 80.8/1000 and 100.2/1000 person-years in non-evacuees and evacuees, respectively. Evacuation was a significant risk factor of CKD incidence after adjusting for age, gender, obesity, hypertension, diabetes, dyslipidemia, smoking, and baseline eGFR [hazard ratio (HR): 1.45; 95% confidence interval (CI) 1.35–1.56]. Evacuation was significantly associated with the incidence of eGFR <60 ml/min/1.73 m2 (HR: 1.48; 95% CI 1.37–1.60), but not with the incidence of proteinuria (HR: 1.21; 95% CI 0.93–1.56). Evacuation was a risk factor associated with CKD incidence after the disaster.
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影响因子：
4.3
作者：
Satoh H;Ohira T;Hosoya M;Sakai A;Watanabe T;Ohtsuru A;Kawasaki Y;Suzuki H;Takahashi A;Kobashi G;Ozasa K;Yasumura S;Yamashita S;Kamiya K;Abe M
通讯作者：
Abe M
福岛Daiichi核电站事故造成的疏散区疏散区的严重心理困扰：福岛健康管理调查。
影响因子：
3.7
作者：
Kunii Y;Suzuki Y;Shiga T;Yabe H;Yasumura S;Maeda M;Niwa S;Otsuru A;Mashiko H;Abe M;Mental Health Group of the Fukushima Health Management Survey
通讯作者：
Mental Health Group of the Fukushima Health Management Survey
影响因子：
4.7
作者：
Yasumura S;Hosoya M;Yamashita S;Kamiya K;Abe M;Akashi M;Kodama K;Ozasa K;Fukushima Health Management Survey Group
通讯作者：
Fukushima Health Management Survey Group
影响因子：
11.1
作者：
Suzuki, Yuriko;Yabe, Hirooki;Abe, Masafumi
通讯作者：
Abe, Masafumi
影响因子：
2.3
作者：
Iseki, Kunitoshi;Asahi, Koichi;Watanabe, Tsuyoshi
通讯作者：
Watanabe, Tsuyoshi