The adherence and illness perception of patients diagnosed with asthma or chronic obstructive pulmonary disease treated with polytherapy using new generation Cyclohaler.
The adherence and illness perception of patients diagnosed with asthma or chronic obstructive pulmonary disease treated with polytherapy using new generation Cyclohaler.
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DOI：
10.5114/pdia.2014.45070
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发表时间：
2014-08
影响因子：
1.4
通讯作者：
Almgren-Rachtan A
中科院分区：
文献类型：
--
作者：
Olszanecka-Glinianowicz M;Almgren-Rachtan A
影响哮喘和慢性阻塞性肺疾病(COPD)患者依从性的因素包括治疗的复杂性、对药物副作用的恐惧、服药方法、给药方案、多药联用、不良事件、对疾病本质及其并发症的了解、对疾病的认知和生活中的优先事项、关于吸入器使用的培训、治疗时间、社会支持和药物可获得性。目的：评估哮喘和慢性阻塞性肺疾病(COPD)患者使用Fantasmino吸入器接受丙酸氟替卡松和富马酸福莫特罗综合治疗的依从性与初步诊断和疾病认知的关系，以及患者和医生对这种治疗形式的意见。一项由肺科医生、过敏专科医生和全科医生进行的问卷调查，涵盖了3618名哮喘患者和2602名COPD患者对新一代环哈乐综合疗法的依从性、疾病认知和意见。第1次访问时，COPD组的依从率低于哮喘组(72.0%vs.61.5%；p<；0.01)。在观察期间，COPD组的粘附率显著增加，仅为61.5%比73.0%；p<；0.01)。两组MMAS-8总分与BIPQ总分呈负相关(分别为R=-0.15p<；0.001和R=-0.24p<；0.001)。在观察期间，在两个研究组中，认为在同一吸入器中同时使用这两种药物极大地促进其使用的患者的百分比显著增加。此外，越来越多的医生认为这一治疗方案有助于对患者进行教育，并减少患者犯下的错误数量。在哮喘和COPD患者中，疾病认知、更年轻的年龄、疾病持续时间和严重程度是坚持使用Fantasmino吸入器使用丙酸氟替卡松和富马酸福莫特罗治疗的预测因素。在观察过程中，患者和医生对使用芬塔斯米诺吸入器使用丙酸氟替卡松和富马酸福莫特罗的积极意见有所增加。
The factors influencing adherence of patients diagnosed with asthma and chronic obstructive pulmonary disease (COPD) include the complexity of the therapy, fear of side effects of drugs, method of taking the drug, dosage regimen, polypharmacy, adverse events, knowledge about the essence of the disease and its complications, illness perception and priorities in life, training on the use of the inhaler, the duration of treatment, social support, and drug availability. To assess the adherence of patients diagnosed with asthma and COPD treated with polytherapy with fluticasone propionate and formoterol fumarate using the Fantasmino inhaler in relation to primary diagnosis and illness perception as well as patients’ and doctors’ opinion about this form of therapy. A questionnaire survey covering adherence, illness perception and opinion about polytherapy using new generation Cyclohaler performed by pulmonologists, allergologists and general practitioners in 3,618 patients with asthma and 2,602 with COPD. On visit 1, a lower adherence rate was observed in COPD than in the asthma group (72.0% vs. 61.5%; p < 0.01). During the observation, the adherence rate increased significantly in the COPD group, only (61.5% vs. 73.0%; p < 0.01). A negative correlation between total MMAS-8 and BIPQ scores was observed in both study groups (R = –0.15; p < 0.001 and R = –0.24; p < 0.001, respectively). During the observation, a percentage of patients who believed that the administration of the two drugs in a single inhaler considerably facilitates their use increased significantly in both study groups. In addition, an increased percentage of doctors believed that this therapeutic option facilitated education of patients and decreased the number of errors made by the patients. The illness perception, younger age, disease duration and severity are predictors of adherence to treatment with fluticasone propionate and formoterol fumarate using the Fantasmino inhaler among patients with asthma and COPD. The positive opinion of patients and doctors about administration of fluticasone propionate and formoterol fumarate using the Fantasmino inhaler increased during observation.
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影响因子：
1.6
作者：
Clark, Noreen M.;Cabana, Michael D.;Kaciroti, Niko
通讯作者：
Kaciroti, Niko
影响因子：
12.4
作者：
Canonica, G. W.;Baena-Cagnani, C. E.;Valovirta, E. J.
通讯作者：
Valovirta, E. J.
影响因子：
5.7
作者：
Sofianou, Anastasia;Martynenko, Melissa;Federman, Alex D.
通讯作者：
Federman, Alex D.
慢性阻塞性肺疾病患者的生活质量感知：初级保健中关于疾病感知作用的横断面研究。
影响因子：
2.9
作者：
Weldam SW;Lammers JW;Heijmans MJ;Schuurmans MJ
通讯作者：
Schuurmans MJ
影响因子：
24.3
作者：
van der Palen, J;Klein, JJ;Seydel, ER
通讯作者：
Seydel, ER