Self-gated free-breathing 3D coronary CINE imaging with simultaneous water and fat visualization.
Self-gated free-breathing 3D coronary CINE imaging with simultaneous water and fat visualization.
复制标题
自我门控的自由呼吸3D冠状动脉成像，同时水和脂肪可视化。
DOI：
10.1371/journal.pone.0089315
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Wang Y
中科院分区：
文献类型：
--
作者：
Liu J;Nguyen TD;Zhu Y;Spincemaille P;Prince MR;Weinsaft JW;Saloner D;Wang Y
本研究的目的是开发一种新技术，用于在自由呼吸期间采集 3 维 (3D) 冠状动脉 CINE 磁共振图像，同时显示水和脂肪，无需外部呼吸或心脏门控。所实施的多回波混合 3D 径向平衡稳态自由进动 (SSFP) 序列具有高效的数据采集能力并且对运动具有鲁棒性。重复采集沿切片编码方向的 k 空间中心，以在不增加扫描时间的情况下导出呼吸和心脏自门信号，从而实现自由呼吸采集。多回波采集允许通过水脂分离进行图像重建，从而改善冠状动脉管腔的可视化。 10名健康受试者在1.5 T下成功成像，达到1.0×1.0×3.0 mm3的空间分辨率，扫描时间约5分钟。所提出的成像技术提供的冠状血管描绘与传统屏气成像和导航门控自由呼吸成像获得的冠状血管描绘相当。
The aim of this study was to develop a novel technique for acquiring 3-dimensional (3D) coronary CINE magnetic resonance images with both water and fat visualization during free breathing and without external respiratory or cardiac gating. The implemented multi-echo hybrid 3D radial balanced Steady-State Free Precession (SSFP) sequence has an efficient data acquisition and is robust against motion. The k-space center along the slice encoding direction was repeatedly acquired to derive both respiratory and cardiac self-gating signals without an increase in scan time, enabling a free-breathing acquisition. The multi-echo acquisition allowed image reconstruction with water-fat separation, providing improved visualization of the coronary artery lumen. Ten healthy subjects were imaged successfully at 1.5 T, achieving a spatial resolution of 1.0×1.0×3.0 mm3 and scan time of about 5 minutes. The proposed imaging technique provided coronary vessel depiction comparable to that obtained with conventional breath-hold imaging and navigator gated free-breathing imaging.
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