Facile preparation of hybrid vesicles loaded with silica nanoparticles via aqueous photoinitiated polymerization-induced self-assembly
Facile preparation of hybrid vesicles loaded with silica nanoparticles via aqueous photoinitiated polymerization-induced self-assembly
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通过水性光引发聚合诱导的自组装轻松制备负载二氧化硅纳米粒子的杂化囊泡
DOI:
10.1039/c7ra02770b
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发表时间:
2017-04
期刊:
影响因子:
3.9
通讯作者:
Zhang Li
中科院分区:
文献类型:
--
作者:
Tan Jianbo;Liu Dongdong;Zhang Xuechao;Huang Chundong;He Jun;Xu Qin;Li Xueliang;Zhang Li
We report a room-temperature photoinitiated polymerization-induced self-assembly (photo-PISA) of 2-hydroxypropyl methacrylate (HPMA) in the presence of silica nanoparticles using a poly(ethylene glycol) methyl ether (mPEG) macromolecular chain transfer agent (macro-CTA). Hybrid vesicles loaded with silica nanoparticles were obtained by this one-pot approach. The solids content of the polymer vesicles can be up to 25% w/w. A control experiment was conducted to prove that free silica nanoparticles can be removed via centrifugation-redispersion. Finally, CO2-responsive hybrid vesicles were prepared by photo-PISA of HPMA and 2-(dimethylamino)ethyl methacrylate (DMAEMA). Silica nanoparticles were subsequently released from the vesicles via CO2 bubbling at room temperature.
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