Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients.
Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients.
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DOI：
10.1111/j.1469-0691.2004.00956.x
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发表时间：
2004-07
期刊：
影响因子：
--
通讯作者：
Sung JJ
中科院分区：
文献类型：
--
作者：
Soo YO;Cheng Y;Wong R;Hui DS;Lee CK;Tsang KK;Ng MH;Chan P;Cheng G;Sung JJ
Treatment of severe acute respiratory syndrome (SARS) is experimental, and the effectiveness of ribavirin–steroid therapy is unclear. Forty SARS patients with progressive disease after ribavirin treatment and 1.5 g of pulsed methylprednisolone were given either convalescent plasma (n = 19) or further pulsed methylprednisolone (n = 21) in a retrospective non‐randomised study. Good clinical outcome was defined as discharge by day 22 following the onset of symptoms. Convalescent plasma was obtained from recovered patients after informed consent. Patients in the plasma group had a shorter hospital stay (p 0.001) and lower mortality (p 0.049) than the comparator group. No immediate adverse effects were observed following plasma infusion.
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影响因子：
6.4
作者：
Mupapa, K;Massamba, M;Muyembe-Tamfum, JJ
通讯作者：
Muyembe-Tamfum, JJ
DOI：
10.1016/s0140-6736(03)13412-5
发表时间：
2003-05-24
期刊：
Lancet (London, England)
影响因子：
--
作者：
Peiris JS;Chu CM;Cheng VC;Chan KS;Hung IF;Poon LL;Law KI;Tang BS;Hon TY;Chan CS;Chan KH;Ng JS;Zheng BJ;Ng WL;Lai RW;Guan Y;Yuen KY;HKU/UCH SARS Study Group
通讯作者：
HKU/UCH SARS Study Group
影响因子：
158.5
作者：
Drosten, C;G端nther, S;Doerr, HW
通讯作者：
Doerr, HW
影响因子：
158.5
作者：
Ksiazek, TG;Erdman, D;Anderson, LJ
通讯作者：
Anderson, LJ
影响因子：
158.5
作者：
Lee, N;Hui, D;Sung, JJY
通讯作者：
Sung, JJY