National prevalence and exposure risk for cockroach allergen in U.S. households.
National prevalence and exposure risk for cockroach allergen in U.S. households.
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DOI：
10.1289/ehp.8561
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发表时间：
2006-04
影响因子：
10.4
通讯作者：
Zeldin DC
中科院分区：
文献类型：
--
作者：
Cohn RD;Arbes SJ Jr;Jaramillo R;Reid LH;Zeldin DC
我们在美国家庭的全国代表性样本中描述了蟑螂过敏原暴露的流行情况，并评估了浓度升高的风险因素。我们使用的数据来自全国住房铅和过敏原调查，这是一项基于人口的横断面调查。参与调查的是831个美国家庭的居民。我们分析了831个美国家庭的过敏原、问卷和观察数据。蟑螂过敏原（Bla g 1）浓度超过2.0 U/g，这是与过敏致敏相关的水平，在美国11%的客厅地板和13%的厨房地板中。在3%的客厅地板和10%的厨房地板中，浓度超过8.0 U/g，这是与哮喘发病率相关的水平。在高层公寓、城市环境、1940年前的建筑和收入低于20，000美元的家庭中观察到浓度升高。当报告或观察到蟑螂问题时，浓度> 8.0 U/g的几率最大，并且随着观察到的蟑螂数量和最近蟑螂活动的迹象而增加。家庭蟑螂过敏原暴露的特点是在全国代表性的背景下。过敏原在许多环境中普遍存在，其水平可能导致过敏性致敏和哮喘发病。可以通过考虑人口统计学和家庭决定因素来评估接触的可能性。
We characterized the prevalence of cockroach allergen exposure in a nationally representative sample of U.S. homes and assessed risk factors for elevated concentrations. We used data from the National Survey of Lead and Allergens in Housing, a population-based cross-sectional survey. Participants were residents of 831 U.S. homes in the survey. We analyzed allergen, questionnaire, and observational data of 831 U.S. homes. Cockroach allergen (Bla g 1) concentrations exceed 2.0 U/g, a level associated with allergic sensitization, in 11% of U.S. living room floors and 13% of kitchen floors. Concentrations exceed 8.0 U/g, a level associated with asthma morbidity, in 3% of living room floors and 10% of kitchen floors. Elevated concentrations were observed in high-rise apartments, urban settings, pre-1940 constructions, and households with incomes < $20,000. Odds of having concentrations > 8.0 U/g were greatest when roach problems were reported or observed and increased with the number of cockroaches observed and with indications of recent cockroach activity. Household cockroach allergen exposure is characterized in a nationally representative context. The allergen is prevalent in many settings, at levels that may contribute to allergic sensitization and asthma morbidity. Likelihood of exposure can be assessed by consideration of demographic and household determinants.
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影响因子：
10.4
作者：
Crain, EF;Walter, M;Stout, JW
通讯作者：
Stout, JW
影响因子：
14.2
作者：
Arbes, SJ;Sever, M;Zeldin, DC
通讯作者：
Zeldin, DC
影响因子：
14.2
作者：
Arbes, SJ;Sever, M;Zeldin, DC
通讯作者：
Zeldin, DC
影响因子：
14.2
作者：
Sarpong, SB;Hamilton, RG;Adkinson, NF
通讯作者：
Adkinson, NF
影响因子：
10.4
作者：
Gehring, U;Triche, E;Leaderer, BP
通讯作者：
Leaderer, BP