Racial and ethnic differences in obesity and overweight as predictors of the onset of functional impairment.

Racial and ethnic differences in obesity and overweight as predictors of the onset of functional impairment.
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DOI:
10.1111/jgs.12605
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发表时间:
2014-01
影响因子:
6.3
通讯作者:
Wu B
Wu B
中科院分区:
医学1区
文献类型:
--
作者:
Wei L;Wu B

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在10年的随访中,研究体重指数(BMI)对功能障碍发病的影响的种族/民族差异。对一项具有全国代表性的美国社区成年人调查的纵向分析。美国健康与退休研究(HRS)的六波(1996-2006)两组HRS参与者年龄≥50岁,基线时无功能障碍(1996年):5884例无行动困难,8484例无日常生活活动(ADLs)困难。行动困难是对行走几个街区、行走一个街区、爬几层楼梯和爬一层楼梯的困难程度的综合衡量。ADL的困难程度是通过穿衣服、洗澡或展示、吃饭和在没有帮助的情况下上下床的困难程度来衡量的。使用广义估计方程(GEE)模型估计基线BMI类别与发生功能障碍风险之间的关系。超重和肥胖是功能损害的重要预测因素。与同样超重和肥胖类别的白人相比,西班牙裔美国人患ADL残疾的可能性分别高出41%和91%。超重和严重肥胖的黑人也比白人更容易患上ADL残疾。在肥胖类别中,西班牙裔人出现ADL困难的风险高于黑人。对于开始的行动困难,在任何BMI类别中,没有发现种族/民族之间的显著差异。黑人和西班牙裔患ADL的风险高于白人,但不存在行动障碍。除了控制体重外,预防措施还应促进运动,以减少功能损害,特别是对风险较高的黑人和西班牙裔人。
To examine racial/ethnic differences in the effects of body mass index (BMI) on the onset of functional impairment over 10 years of follow-up. Longitudinal analyses of a cohort from a nationally representative survey of community-dwelling American adults. Six waves (1996-2006) of US Health and Retirement Study (HRS). Two groups of HRS participants aged ≥50 without functional impairment at baseline (1996): 5,884 with no mobility difficulty, and 8,484 with no Activities of Daily Living (ADLs) difficulty. Mobility difficulty was a composite measure of difficulty in walking several blocks, walking one block, climbing several flights of stairs, and climbing one floor of stairs. ADL difficulty was measured by difficulty in dressing, bathing or showing, eating, and getting in or out of bed without help. The association between the baseline BMI categories and risk to develop functional impairment was estimated using generalized estimating equations (GEE) models. Overweight and obesity were significant predictors for functional impairment. Compared to the Whites in the same overweight and obese categories, Hispanics were 41% and 91% more likely to develop ADL disability. Blacks in the overweight and severely obese categories were also more likely than their White counterparts to develop ADL disability. Risk of developing ADL difficulty was higher for Hispanics than for Blacks in the obese category. For onset of mobility difficulty, no significant differences were found across racial/ethnic groups within any BMI Category. Blacks and Hispanics were at higher risk than Whites for ADL but not mobility impairment. In addition to weight control, prevention efforts should promote exercise to reduce functional impairment, especially for Blacks and Hispanics, who are at higher risk.
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