Circular array transducer based-photoacoustic/ultrasonic endoscopic imaging with tunable ring-beam excitation.
Circular array transducer based-photoacoustic/ultrasonic endoscopic imaging with tunable ring-beam excitation.
复制标题
基于环形阵列换能器的可调环束激励光声/超声内窥镜成像。
DOI：
10.1016/j.pacs.2022.100441
复制
发表时间：
2023-03
期刊：
影响因子：
7.9
通讯作者：
Gong, Xiaojing
中科院分区：
文献类型：
--
作者：
Xie, Zhihua;Liu, Jiamei;Ren, Yaguang;Huang, Jiqing;Lin, Riqiang;Wang, Xiatian;Tan, Qingyuan;Lv, Shengmiao;Song, Liang;Liu, Chengbo;Ma, Teng;Gong, Xiaojing
关键词：
光声/超声内窥镜成像被认为是一种有效的方法，以实现准确的检测肠道疾病，同时提供功能和结构的信息。与传统的单换能器、激光光斑进行信号检测和光激励的内窥镜相比，光声/超声内窥镜探头采用圆形阵列换能器和环形激光束，避免了机械扫描点对点带来的不稳定性，提供了高精度和高效率的双模态成像。同时，考虑到临床上肠道的复杂形态环境，开发具有足够宽成像距离范围的探头尤为重要。本文研制了一种小型的圆形光声/超声内窥探头，利用光纤、透镜和自制轴棱锥组，产生相对集中的环形激光束，实现360°高效率激发。此外，激光环的大小可以方便地调整，通过改变光纤透镜的距离，以确保探头在各种和复杂的肠道形态环境的潜在适用性。体模实验结果表明，成像距离范围足够宽，覆盖从12 mm到30 mm。此外，还证明了在离体实验中使用5 mJ的激发能量在7 mm的组织深度处分子探针的光声信号的可达性，显示了探针的高光学激发效率。
Photoacoustic/ultrasound endoscopic imaging is regarded as an effective method to achieve accurate detection of intestinal disease by offering both the functional and structural information, simultaneously. Compared to the conventional endoscopy with single transducer and laser spot for signal detection and optical excitation, photoacoustic/ultrasound endoscopic probe using circular array transducer and ring-shaped laser beam avoids the instability brought by the mechanical scanning point-to-point, offering the dual-modality imaging with high accuracy and efficiency. Meanwhile, considering the complex morphological environments of intestinal tracts in clinics, developing the probe having sufficient wide imaging distance range is especially important. In this work, we develop a compact circular photoacoustic/ultrasonic endoscopic probe, using the group of fiber, lens and home-made axicon, to generate relatively concentrated ring-shaped laser beam for 360° excitation with high efficiency. Furthermore, the laser ring size can be tuned conveniently by changing the fiber-lens distance to ensure the potential applicability of the probe in various and complex morphological environments of intestines. Phantom experimental results demonstrate imaging distance range wide enough to cover from 12 mm to 30 mm. In addition, the accessibility of the photoacoustic signals of molecular probes in ex vivo experiments at the tissue depth of 7 mm using excitation energy of 5 mJ has also been demonstrated, showing a high optical excitation efficiency of the probe.
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DOI：
10.14366/usg.14062
发表时间：
2015-04
期刊：
Ultrasonography (Seoul, Korea)
影响因子：
--
作者：
Kim J;Lee D;Jung U;Kim C
通讯作者：
Kim C
DOI：
10.3390/diagnostics4020057
发表时间：
2014-05-05
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Tsai TH;Fujimoto JG;Mashimo H
通讯作者：
Mashimo H
影响因子：
7.4
作者：
Guo Tao;Lu Xing-hua;Qian Jia-ming
通讯作者：
Qian Jia-ming
影响因子：
4.3
作者：
Wang C;Lu YF;Cai CM;Xiang HZ;Zheng G
通讯作者：
Zheng G
影响因子：
4.2
作者：
Berretta, Roberto;Patrelli, Tito Silvio;Gizzo, Salvatore
通讯作者：
Gizzo, Salvatore