Searching for differentially expressed gene combinations.
Searching for differentially expressed gene combinations.
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DOI:
10.1186/gb-2005-6-10-r88
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发表时间:
2005
期刊:
影响因子:
12.3
通讯作者:
Parmigiani G
中科院分区:
文献类型:
--
作者:
Dettling M;Gabrielson E;Parmigiani G
CorScor is a novel approach to identifying gene pairs with joint differential expression. It can be used to detect phenotype-related dependencies and interactions among genes. We propose 'CorScor', a novel approach for identifying gene pairs with joint differential expression. This is defined as a situation with good phenotype discrimination in the bivariate, but not in the two marginal distributions. CorScor can be used to detect phenotype-related dependencies and interactions among genes. Our easily interpretable approach is scalable to current microarray dimensions and yields promising results on several cancer-gene-expression datasets.
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影响因子:
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通讯作者:
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DOI:
10.1073/pnas.091062498
发表时间:
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影响因子:
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作者:
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通讯作者:
Chu, G
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