A Brief Overview of the Cerebrospinal Fluid System and Its Implications for Brain and Spinal Cord Diseases.
A Brief Overview of the Cerebrospinal Fluid System and Its Implications for Brain and Spinal Cord Diseases.
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DOI：
10.3389/fnhum.2021.737217
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发表时间：
2021
影响因子：
2.9
通讯作者：
Pedersen M
中科院分区：
文献类型：
--
作者：
Wichmann TO;Damkier HH;Pedersen M
对脑脊液（CSF）系统的全面了解对于我们了解中枢神经系统（CNS）内的健康和疾病至关重要。CSF系统是指参与CSF产生、移动和吸收的所有成分。近年来，广泛的研究极大地提高了对健康和疾病中CSF系统的理解。然而，仍有几个方面有待充分澄清，特别是沿着脊髓，因为研究的优势集中在大脑。本文简要总结了CSF系统及其对CNS疾病的影响，并强调了需要进一步研究的知识差距。
A comprehensive understanding of the cerebrospinal fluid (CSF) system is essential for our understanding of health and disease within the central nervous system (CNS). The system of CSF refers to all components involved in CSF production, movement, and absorption. In recent years, extensive research has resulted in vastly improved understanding of the CSF system in health and disease. Yet, several aspects remain to be fully clarified, notably along the spinal cord as the preponderance of research has focused on the brain. This review briefly summarizes the CSF system and its implications for CNS diseases and highlights the knowledge gaps that require further research.
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