Effect of different levels of hydrolysable tannin intake on the reproductive hormones and serum biochemical indices in healthy female rats.
Effect of different levels of hydrolysable tannin intake on the reproductive hormones and serum biochemical indices in healthy female rats.
复制标题
DOI：
10.1038/s41598-020-77672-0
复制
发表时间：
2020-11-26
影响因子：
4.6
通讯作者：
Umbreen H
中科院分区：
文献类型：
--
作者：
Manzoor F;Nisa MU;Hussain HA;Ahmad N;Umbreen H
The present work aimed to find out the effect of different levels of hydrolysable tannin (HT) on serum hormonal profile, biochemical indices, lipid profile, apparent digestibility of nutrients and body weight gain in healthy female rats. Forty five adult healthy female rats of 8 weeks old were randomly divided into five equal groups. Different doses of HT 0, 0.5, 1, 1.5 and 2% were administered daily to each rats group on the body weight basis for 6 weeks. The results had shown the reduction trend (p < 0.05) in the blood glucose, serum cholesterol, low density lipoprotein, testosterone, prolactin, ghrelin, total oxidative stress and serum iron levels; while an improvement (p < 0.05) was seen in serum follicle stimulating hormone, progesterone, luteinizing hormone, high density lipoprotein, IgM and total antioxidant capacity. However, no effect (p > 0.05) was noticed in serum IgG, protein, estrogen and calcium levels. A significant reduction (p < 0.05) was seen in the apparent nutrient digestibility and body weight gain. The results had shown improvement in the feed conversion ratio (p < 0.05) but non-significant decrease (p > 0.05) in the feed intake. The findings showed that HT had healthy effects on the serum biochemical indices and reproductive hormonal profile but had a negative impact on the nutrient digestibility. Thus, the study concluded that HT could be used as an herbal medicine for the treatment of leading metabolic and infertility diseases like obesity and polycystic ovarian syndrome in females.
登录
查看更多内容
影响因子：
2.9
作者：
BAUER, PJ
通讯作者：
BAUER, PJ
影响因子：
--
作者：
Ihedioha, J. I.;Noel-Uneke, O. A.;Ihedioha, T. E.
通讯作者：
Ihedioha, T. E.
影响因子：
6.1
作者：
Kim, Hyunsook;Bartley, Glenn E.;Yokoyama, Wallace
通讯作者：
Yokoyama, Wallace
影响因子：
6.1
作者：
Anderson, RA;Polansky, MM
通讯作者：
Polansky, MM
影响因子：
1.6
作者：
Afsana, K;Shiga, K;Hara, H
通讯作者：
Hara, H