Cardiology clinic patient attitudes toward and potential personal utility of genetic testing: Findings from a unique multiracial clinical sample.
Cardiology clinic patient attitudes toward and potential personal utility of genetic testing: Findings from a unique multiracial clinical sample.
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DOI：
10.1002/jgc4.1573
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发表时间：
2022-08
影响因子：
1.9
通讯作者：
Aggarwal, Neelum T.
中科院分区：
文献类型：
--
作者：
Erickson, Claire M.;Clark, Lindsay R.;Umucu, Emre;Vo, Nhi H.;Volgman, Annabelle Santos;Chin, Nathaniel A.;Ketchum, Fred B.;Jones, Carolyn H.;Gleason, Carey E.;Aggarwal, Neelum T.
随着人们对疾病风险遗传性的了解越来越多，人们越来越多地探索基因检测在心血管医学中的应用。尽管检测可以提供更个性化的风险分层，但有关心脏病患者对基因检测的知识、态度和信念的信息却很少。主要从心脏病诊所招募的参与者 (n = 530) 填写了一份包含 41 项的书面调查问卷，评估对基因检测的知识、信念和态度、考虑基因检测的动机和反对因素，以及假设基因检测风险分层后行为改变的感知可能性。路径分析用于测试假设模型，预测进行基因测试并在基因测试后改变行为的可能性。患者群体为中老年（59.0 ± 14.5 岁），大多数为女性（61.5%），大约一半的人拥有学士学位。 58.1% 的参与者自认为是白人，25.7% 是非裔美国人或黑人，6.8% 是西班牙人、拉丁裔或拉美裔人，3.0% 是亚裔或太平洋岛民，0.5% 是美洲原住民。性别（女性）和更长的教育年限与更多的基因检测知识有关。种族认同和受教育年限与基因检测的信念有关。信念而非知识与更积极的态度和更高的进行基因检测的可能性有关。积极的态度与更强的个人控制感（PPC）有关。此外，态度和 PPC 与基因检测后生活方式改变的可能性较高有关。这些结果凸显了将种族社区的经验纳入教育/咨询工作的必要性。大多数教育咨询工作缺乏对健康或信仰的社会决定因素的细致讨论。除了事实信息之外，教育咨询还必须解决人们的信念、担忧以及交叉的经历和身份，这些因素塑造了患者与不断发展的医疗保健和个性化医疗格局的关系。
As more is understood about the hereditary nature of disease risk, the utility of genetic testing within cardiovascular medicine is increasingly being explored. Although testing may afford more personalized risk stratification, there is a paucity of information regarding patient knowledge, attitudes, and beliefs toward genetic testing among cardiology patients. Participants (n = 530) recruited primarily from a cardiology clinic filled out a 41‐item written questionnaire assessing knowledge, beliefs, and attitudes toward genetic testing, motivators and detractors for considering genetic testing, and perceived likelihood for behavior change after hypothetical genetic testing risk stratification. Path analysis was used to test the hypothetical models predicting the likelihood of getting a genetic test and making behavior changes following genetic testing. The patient population was late‐middle‐aged (59.0 ± 14.5 years), majority women (61.5%), and about half reported having a bachelor's degree. 58.1% of participants self‐identified as White, 25.7% as African American or Black, 6.8% as Spanish, Latino, or Hispanic, 3.0% as Asian or Pacific Islander, and 0.5% as Native American. Gender (being a woman) and more years of education were related to greater knowledge about genetic testing. Racial identity and years of education were related to beliefs about genetic testing. Beliefs, but not knowledge, were related to more positive attitudes and a higher likelihood of pursuing genetic testing. Positive attitudes were related to greater perceived personal control (PPC). Furthermore, attitudes and PPC were related to higher likelihood of lifestyle change after genetic testing. These results highlight the need to integrate the experiences of racialized communities into education/counseling efforts. Most educational counseling efforts lack a nuanced discussion of social determinants of health or beliefs. In addition to factual information, educational counseling must also address people's beliefs, concerns, and the intersecting experiences and identities, which shape patients' relationships with the evolving landscape of healthcare and personalized medicine.
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影响因子：
7.4
作者：
Musunuru, Kiran;Hershberger, Ray E.;Sturm, Amy C.
通讯作者：
Sturm, Amy C.
影响因子：
2.7
作者：
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通讯作者：
Catalano, Denise
DOI：
10.1080/10705511.2014.937847
发表时间：
2015-07-03
影响因子：
6
作者：
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通讯作者：
Epskamp, Sacha
DOI：
10.1186/1479-5868-9-78
发表时间：
2012-06-22
期刊：
The international journal of behavioral nutrition and physical activity
影响因子：
--
作者：
Teixeira PJ;Carraça EV;Markland D;Silva MN;Ryan RM
通讯作者：
Ryan RM
影响因子：
4.2
作者：
Freedman, Barry I.;Fletcher, Alison J.;King, Nancy M. P.
通讯作者：
King, Nancy M. P.