Lymphatic vessels in health and disease.

Lymphatic vessels in health and disease.
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健康和疾病中的淋巴管。

DOI:
10.1002/wsbm.1201
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发表时间:
2013-01
影响因子:
7.9
通讯作者:
Padera, Timothy P.
Padera, Timothy P.
中科院分区:
医学3区
文献类型:
--
作者:
Kesler, Cristina T.;Liao, Shan;Munn, Lance L.;Padera, Timothy P.

文献摘要

参考文献

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淋巴管系统在组织液平衡、免疫防御、新陈代谢和肿瘤转移等方面发挥着重要作用。在成人中,淋巴管的形成和重塑主要发生在炎症、黄体发育、伤口愈合和肿瘤生长期间。与血液循环不同,单向流动是由心脏的泵送作用维持的,淋巴管本身固有的泵送作用是淋巴管流动的重要驱动因素。本文综述了控制淋巴生理的关键成分。
The lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism and cancer metastasis. In adults, lymphatic vessel formation and remodeling occurs primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth. Unlike the blood circulation, where unidirectional flow is sustained by the pumping actions of the heart, pumping actions intrinsic to the lymphatic vessels themselves are important drivers of lymphatic flow. This review summarizes critical components that control lymphatic physiology.
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