Barriers to Oral HIV Pre-exposure Prophylaxis (PrEP) Adherence Among Pregnant and Post-partum Women from Cape Town, South Africa.
Barriers to Oral HIV Pre-exposure Prophylaxis (PrEP) Adherence Among Pregnant and Post-partum Women from Cape Town, South Africa.
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DOI：
10.1007/s10461-022-03652-2
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发表时间：
2022-09
影响因子：
4.4
通讯作者：
Joseph Davey DL
中科院分区：
文献类型：
--
作者：
Beesham I;Dovel K;Mashele N;Bekker LG;Gorbach P;Coates TJ;Myer L;Joseph Davey DL
东部和南部非洲的顺性别妇女，特别是孕妇和产后妇女，面临感染艾滋病毒的高风险，令人无法接受。口服暴露前预防（PrEP）是一种有效的艾滋病毒预防干预措施，可以减少艾滋病毒感染和垂直传播。在这项定性研究中，我们采访了来自南非开普敦的21名产后妇女，她们在怀孕期间开始了PrEP，并自我报告PrEP依从性低或错过了> 1次PrEP随访收集。我们发现了PrEP继续和/或坚持的多个重叠障碍。个人因素包括忘记每天服用PrEP，当PrEP应该服用时离家，预期的耻辱和PrEP使用的有限披露。女性还报告了与药物相关的因素，例如副作用以及在怀孕期间和产后期间除了其他药片之外还必须服用PrEP。与设施有关的障碍包括PrEP收集的后勤问题，特别是在产前护理之外的情况下，以及运输和财政障碍。
Cisgender women, particularly pregnant and postpartum women in Eastern and Southern Africa, face an unacceptably high risk of HIV acquisition. Oral pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention that can reduce HIV acquisition and vertical transmission. In this qualitative study, we interviewed 21 postpartum women from Cape Town, South Africa who initiated PrEP during pregnancy and who self-reported low PrEP adherence or missed > 1 PrEP follow-up collection. We identified multiple overlapping barriers to PrEP continuation and/or adherence. Individual factors included forgetting to take PrEP daily, being away from home when PrEP should be taken, anticipated stigma and limited disclosure of PrEP use. Women also reported pill-related factors such as side effects and having to take PrEP in addition to other tablets during pregnancy and the postpartum period. Facility-related barriers included logistics around PrEP collection especially when not in antenatal care, as well as transport and financial barriers.
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影响因子：
4.4
作者：
Beesham I;Heffron R;Evans S;Baeten JM;Smit J;Beksinska M;Mansoor LE
通讯作者：
Mansoor LE
影响因子：
6
作者：
Velloza, Jennifer;Khoza, Nomhle;Delany-Moretlwe, Sinead
通讯作者：
Delany-Moretlwe, Sinead
影响因子：
3.7
作者：
Zimba, Chifundo;Maman, Suzanne;Chi, Benjamin H.
通讯作者：
Chi, Benjamin H.
DOI：
10.1097/qad.0000000000001922
发表时间：
2018-08-24
期刊：
AIDS (London, England)
影响因子：
--
作者：
Pyra M;Anderson PL;Hendrix CW;Heffron R;Mugwanya K;Haberer JE;Thomas KK;Celum C;Donnell D;Marzinke MA;Bukusi EA;Mugo NR;Asiimwe S;Katabira E;Baeten JM;Partners Demonstration Study Team
通讯作者：
Partners Demonstration Study Team
影响因子：
3.7
作者：
Guest, Greg;Namey, Emily;Chen, Mario
通讯作者：
Chen, Mario