Inside information: the unique features of visceral sensation.
Inside information: the unique features of visceral sensation.
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DOI：
10.1124/mi.8.5.9
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发表时间：
2008-10
影响因子：
--
通讯作者：
Gebhart GF
中科院分区：
文献类型：
--
作者：
Robinson DR;Gebhart GF
大多数关于疼痛和伤害感受器的文字和信仰都源于对“躯体”（非内脏）感觉系统的研究。因此，内脏疼痛的独特特征往往被忽视。在临床上，对内脏疼痛的治疗通常很差，用于治疗躯体疼痛的药物通常对内脏产生不良影响。由于这些原因，我们需要更好地了解内脏感觉神经元，尤其是内脏伤害感受器。这篇综述提供了内脏和非内脏传入神经在功能、形态和生化方面的差异的证据，重点是潜在的伤害感受作用，并考虑了内脏机械感觉的一些潜在机制。
Most of what is written and believed about pain and nociceptors originates from studies of the “somatic” (non-visceral) sensory system. As a result, the unique features of visceral pain are often overlooked. In the clinic, the management of visceral pain is typically poor, and drugs that are used with some efficacy to treat somatic pain often present unwanted effects on the viscera. For these reasons, a better understanding of visceral sensory neurons—particularly visceral nociceptors—is required. This review provides evidence of functional, morphological, and biochemical differences between visceral and non-visceral afferents, with a focus on potential nociceptive roles, and also considers some of the potential mechanisms of visceral mechanosensation.
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DOI：
10.1016/s0165-1838(97)00032-5
发表时间：
1997-07-14
期刊：
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
影响因子：
--
作者：
CallsenCencic, P;Mense, S
通讯作者：
Mense, S
影响因子：
29.4
作者：
Brierley, SM;Jones, RCW;Blackshaw, LA
通讯作者：
Blackshaw, LA
影响因子：
3.5
作者：
Brierley, SM;Jones, RCW;Blackshaw, LA
通讯作者：
Blackshaw, LA
影响因子：
--
作者：
Djouhri, L;Lawson, SN
通讯作者：
Lawson, SN
影响因子：
5.5
作者：
Brierley, SM;Carter, R;Blackshaw, LA
通讯作者：
Blackshaw, LA