Functional Neuroimaging in Traumatic Brain Injury: From Nodes to Networks.
Functional Neuroimaging in Traumatic Brain Injury: From Nodes to Networks.
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创伤性脑损伤中的功能神经影像学：从节点到网络。
DOI：
10.3389/fneur.2017.00407
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发表时间：
2017
影响因子：
3.4
通讯作者：
Medaglia JD
中科院分区：
文献类型：
--
作者：
Medaglia JD
自功能磁共振成像 (fMRI) 发明以来，对健康和临床样本进行的数千项研究启发了我们对人脑认知组织以及脑部疾病和损伤后神经塑性变化的理解。研究越来越多地涉及植根于复杂系统理论的分析和应用于临床样本的分析。考虑到现有方法的复杂性，有必要对网络技术的理论动机及其与传统方法和理论的关系进行简明描述。为此，本综述涉及使用功能磁共振成像来了解人脑的基本认知功能和功能障碍，从强调大脑中的基本单元（或“节点”）到大脑网络内部和之间的相互作用。首先，介绍了受伤大脑科学研究中的主要主题和理论问题，以将这些分析置于背景中，特别是有关功能性“大脑重组”的分析。然后，使用图论和相关方法从体素水平到系统水平的分析方法被回顾为检查 TBI 后神经认知过程的补充方法。接下来，讨论与功能重组假设相关的一些主要发现。最后，从理论、分析和转化方面讨论了神经创伤功能网络分析中的主要开放问题。
Since the invention of functional magnetic resonance imaging (fMRI), thousands of studies in healthy and clinical samples have enlightened our understanding of the organization of cognition in the human brain and neuroplastic changes following brain disease and injury. Increasingly, studies involve analyses rooted in complex systems theory and analysis applied to clinical samples. Given the complexity in available approaches, concise descriptions of the theoretical motivation of network techniques and their relationship to traditional approaches and theory are necessary. To this end, this review concerns the use of fMRI to understand basic cognitive function and dysfunction in the human brain scaling from emphasis on basic units (or “nodes”) in the brain to interactions within and between brain networks. First, major themes and theoretical issues in the scientific study of the injured brain are introduced to contextualize these analyses, particularly concerning functional “brain reorganization.” Then, analytic approaches ranging from the voxel level to the systems level using graph theory and related approaches are reviewed as complementary approaches to examine neurocognitive processes following TBI. Next, some major findings relevant to functional reorganization hypotheses are discussed. Finally, major open issues in functional network analyses in neurotrauma are discussed in theoretical, analytic, and translational terms.
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DOI：
10.1177/1073858416667720
发表时间：
2017-10
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Bassett DS;Bullmore ET
通讯作者：
Bullmore ET
影响因子：
5.3
作者：
Achard, S;Salvador, R;Bullmore, ET
通讯作者：
Bullmore, ET
影响因子：
5.7
作者：
Bassett, Danielle S.;Nelson, Brent G.;Mueller, Bryon A.;Camchong, Jazmin;Lim, Kelvin O.
通讯作者：
Lim, Kelvin O.
影响因子：
16.2
作者：
Burda JE;Sofroniew MV
通讯作者：
Sofroniew MV
影响因子：
5.7
作者：
Caeyenberghs, Karen;Verhelst, Helena;Wilson, Peter H.
通讯作者：
Wilson, Peter H.