Contingency management for alcohol use disorder reduces cannabis use among American Indian and Alaska Native adults.

Contingency management for alcohol use disorder reduces cannabis use among American Indian and Alaska Native adults.
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DOI:
10.1016/j.jsat.2021.108693
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发表时间:
2022-06
影响因子:
3.9
通讯作者:
McDonell, Michael G.
McDonell, Michael G.
中科院分区:
医学2区
文献类型:
--
作者:
Hirchak, Katherine A.;Lyons, Abram J.;Herron, Jalene L.;Kordas, Gordon;Shaw, Jennifer L.;Jansen, Kelley;Avey, Jaedon P.;McPherson, Sterling M.;Donovan, Dennis;Roll, John;Buchwald, Dedra;Ries, Richard;McDonell, Michael G.

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确定针对酒精戒断的文化量身定制的应急管理(CM)干预是否会对美国印第安人和阿拉斯加原住民(AI/AN)成年人的大麻使用产生二次影响。研究小组进行了这一次要数据分析,利用来自三个人工智能/人工智能服务组织中酒精使用CM的随机对照试验的数据来检查大麻戒断情况。158名成年人符合随机化标准(即,在4周的预随机化观察期,提交50%或更多的尿液样本,并进行一次酒精阳性尿检)。在随机分组后的12周内,参与者获得了提交葡萄糖醛酸乙酯尿液测试阴性(EtG < 150 ng/mL, CM组)或提交尿液样本的奖励,而不管禁欲与否(非偶然[NC]对照组)。广义线性混合效应模型评估了干预期间大麻戒断的组间差异,并通过尿四氢大麻酚阴性试验(11-no -delta-9-四氢大麻酚-9-羧酸<50 ng/mL)进行验证。在基线时,42.2% (n = 35)的NC组参与者和40.0% (n = 30)的CM组参与者尿检呈大麻阳性。大麻尿检阴性患者存在时间交互作用的整体干预(χ2 = 13.40, p = 0.001)。与NC组相比,CM组在干预期出现大麻尿检阴性的几率是NC组的3.92倍(95% CI: 1.23-12.46),在干预期结束时出现大麻尿检阴性的几率是NC组的5.13倍(95% CI: 1.57-16.76)。CM解决酒精滥用问题可能是减少AI/ an成人使用大麻的有效策略。ClinicalTrials.gov编号,标识符:NCT02174315
Determine whether a culturally tailored contingency management (CM) intervention targeting alcohol abstinence resulted in secondary effects on cannabis use among American Indian and Alaska Native (AI/AN) adults. The research team conducted this secondary data analysis to examine cannabis abstinence using data from a randomized control trial of CM for alcohol use among three AI/AN-serving organizations. One hundred and fifty-eight adults met the randomization criteria (i.e., submission of 50% or more urine samples and one alcohol-positive urine test during a 4-week, pre-randomization, observation period). For 12 weeks after randomization, participants received incentives for submitting a urine test negative for ethyl glucuronide (EtG < 150 ng/mL, CM group) or incentives for submitting a urine sample regardless of abstinence (Non-contingent [NC] Control group). Generalized linear mixed effects models assessed group differences in cannabis abstinence during the intervention, verified by urine tetrahydrocannabinol negative tests (11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid <50 ng/mL). At baseline, 42.2% (n = 35) of participants in the NC group and 40.0% (n = 30) of those in the CM group had a cannabis positive urine test. An overall intervention by time interaction was detected for a cannabis negative urine test (χ2 = 13.40, p = 0.001). Compared to the NC group, the CM group had 3.92 (95% CI:1.23–12.46) times higher odds of having a cannabis negative urine test during the intervention period and 5.13 (95% CI:1.57–16.76) times higher odds of having a negative cannabis test at the end of intervention period. CM addressing alcohol misuse may be an effective strategy for decreasing cannabis use among AI/AN adults. ClinicalTrials.gov number, Identifier: NCT02174315
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发表时间: 2021-06
期刊: Addiction (Abingdon, England)
影响因子: --
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发表时间: 1999-03-01
期刊: JOURNAL OF STUDIES ON ALCOHOL
影响因子: --
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DOI: 10.1016/j.psychres.2017.11.070
发表时间: 2018-02-01
影响因子: 11.3
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影响因子: 3.9
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