Racial/Ethnic Differences in Gestational Diabetes Prevalence and Contribution of Common Risk Factors.
Racial/Ethnic Differences in Gestational Diabetes Prevalence and Contribution of Common Risk Factors.
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DOI：
10.1111/ppe.12209
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发表时间：
2015-09
影响因子：
2.8
通讯作者：
Palaniappan LP
中科院分区：
文献类型：
--
作者：
Pu J;Zhao B;Wang EJ;Nimbal V;Osmundson S;Kunz L;Popat RA;Chung S;Palaniappan LP
白宫、美国心脏协会、医疗保健研究和质量机构以及国家心肺血液研究所最近都承认，有必要对亚裔美国人进行分类，以更好地了解这个异质种族群体。本研究旨在评估亚洲亚组（亚洲印度人、中国人、菲律宾人、日本人、韩国人和越南人）、西班牙裔、非西班牙裔黑人和非西班牙裔白人中妊娠期糖尿病（GDM）风险因素相对贡献的种族/民族差异。通过加州州出生证明记录确定了2007-2012年的孕妇，并将其与北方加州一家大型混合付款人门诊医疗机构的电子健康记录相关联（n = 24 195）。计算特定种族/民族的相对风险和人群归因分数（PAF），以评估高龄产妇、超重/肥胖（疾病控制和预防中心（CDC）标准和世界卫生组织（WHO）/美国糖尿病协会（ADA）亚洲人的体重指数临界值）、2型糖尿病家族史和外国出生状态的贡献。GDM在亚洲印度人中最普遍（19.3%）。所有种族/民族组的相对风险相似。高龄产妇在非西班牙裔白人（22.5%）和西班牙裔（22.7%）中有较高的PAF。同时，在亚洲亚组中，家族史（亚洲印度人22.6%，中国人22.9%）和外国出生状态（中国人40.2%，菲律宾人30.2%）具有较高的PAF。当应用WHO/ADA临界点时，超重/肥胖是非西班牙裔白人、西班牙裔、亚洲印第安人和菲律宾人最重要的GDM风险因素。高龄产妇是研究的唯一一个受种族/民族影响的风险因素，非西班牙裔白色和西班牙裔妇女比其他种族/民族群体受到更大的不利影响。超重/肥胖、高龄产妇、2型糖尿病家族史和外籍身份是GDM的重要危险因素。这些风险因素的相对贡献因人种/种族而异，主要是由于这些风险因素的人群患病率差异。
The White House, the American Heart Association, the Agency for Healthcare Research and Quality, and the National Heart, Lung and Blood Institute have all recently acknowledged the need to disaggregate Asian American subgroups to better understand this heterogeneous racial group. This study aims to assess racial/ethnic differences in relative contribution of risk factors of gestational diabetes mellitus (GDM) among Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese), Hispanics, non-Hispanic blacks, and nonHispanic whites. Pregnant women in 2007–2012 were identified through California state birth certificate records and linked to the electronic health records in a large mixed-payer ambulatory care organisation in Northern California (n = 24 195). Relative risk and population attributable fraction (PAF) for specific racial/ethnic groups were calculated to assess the contributions of advanced maternal age, overweight/obesity (Centers for Disease Control and Prevention (CDC) standards and World Health Organization (WHO)/American Diabetes Association (ADA) body mass index cut-offs for Asians), family history of type 2 diabetes, and foreign-born status. GDM was most prevalent among Asian Indians (19.3%). Relative risks were similar across all race/ethnic groups. Advanced maternal age had higher PAFs in non-Hispanic whites (22.5%) and Hispanics (22.7%). Meanwhile family history (Asian Indians 22.6%, Chinese 22.9%) and foreign-borne status (Chinese 40.2%, Filipinos 30.2%) had higher PAFs in Asian subgroups. Overweight/obesity was the most important GDM risk factor for non-Hispanic whites, Hispanics, Asian Indians, and Filipinos when the WHO/ADA cut-off points were applied. Advanced maternal age was the only risk factor studied that was modified by race/ethnicity, with non-Hispanic white and Hispanic women being more adversely affected than other racial/ethnic groups. Overweight/obesity, advanced maternal age, family history of type 2 diabetes, and foreign-borne status are important risk factors for GDM. The relative contributions of these risk factors differ by race/ethnicity, mainly due to differences in population prevalence of these risk factors.
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影响因子：
16.2
作者：
Hedderson M;Ehrlich S;Sridhar S;Darbinian J;Moore S;Ferrara A
通讯作者：
Ferrara A
影响因子：
16.2
作者：
Hsu WC;Araneta MR;Kanaya AM;Chiang JL;Fujimoto W
通讯作者：
Fujimoto W
影响因子：
16.2
作者：
Lee, Anna J.;Hiscock, Richard J.;Permezel, Michael
通讯作者：
Permezel, Michael
影响因子：
2.3
作者：
Spiegelman, D.;Hertzmark, E.;Wand, H. C.
通讯作者：
Wand, H. C.
影响因子：
12.7
作者：
Thorpe, LE;Berger, D;Frieden, TR
通讯作者：
Frieden, TR